Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.50 |
| ▸ | APP | P05067 | 4/20 | 0.50 |
| ▸ | SNCA | P37840 | 4/20 | 0.50 |
| ▸ | METAP1 | P53582 | 1/20 | 0.48 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11142869 | 0.90 | MAPT (0.51) | MAPTAPPSNCAMETAP1AMY1A | |
| SCHEMBL11148683 | 0.82 | METAP1 (0.53) | MAPTAPPSNCAMETAP1AMY1A | |
| SCHEMBL11153567 | 0.76 | MAPT (0.43) | MAPTTDP1ALDH1A1LMNAKMT2A | |
| SCHEMBL11149380 | 0.76 | METAP1 (0.49) | MAPTAPPSNCAMETAP1AMY1A | |
| SCHEMBL11146842 | 0.75 | NR1H4 (0.60) | MAPTMETAP1ALDH1A1LMNAAKR1B1 | |
| SCHEMBL11146269 | 0.72 | MEN1 (0.58) | MAPTAPPSNCAMETAP1AMY1A | |
| SCHEMBL125192 | 0.71 | KMT2A (0.64) | MAPTAPPSNCAMETAP1TDP1 | |
| SCHEMBL11147680 | 0.71 | TNFRSF1A (0.44) | MAPTTDP1ALDH1A1LMNAKMT2A | |
| SCHEMBL8090142 | 0.71 | ACHE (0.62) | ALDH1A1KMT2AMEN1 | |
| SCHEMBL14015181 | 0.70 | ALDH1A1 (0.54) | MAPTTDP1ALDH1A1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4389477-A | Photoconductive composition sensitized by a thiobarbituric acid derivative | FUJI PHOTO FILM CO., LTD. (JP) | 1983-06-21 | — | — | US | disclosed |