Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP1 | P53582 | 1/20 | 0.49 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 8/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | APP | P05067 | 4/20 | 0.43 |
| ▸ | SNCA | P37840 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | USP18 | Q9UMW8 | 1/20 | 0.40 |
| ▸ | UCHL5 | Q9Y5K5 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11148683 | 0.81 | METAP1 (0.53) | METAP1AMY1ATDP1MAPTALDH1A1 | |
| SCHEMBL11142869 | 0.77 | MAPT (0.51) | METAP1AMY1ATDP1MAPTALDH1A1 | |
| SCHEMBL11147292 | 0.76 | MAPT (0.50) | METAP1AMY1ATDP1MAPTALDH1A1 | |
| SCHEMBL11145691 | 0.75 | TDP1 (0.43) | TDP1MAPTALDH1A1KMT2APOLB | |
| SCHEMBL11146269 | 0.73 | MEN1 (0.58) | METAP1AMY1ATDP1MAPTALDH1A1 | |
| SCHEMBL11274474 | 0.69 | MAPT (0.64) | METAP1MAPTALDH1A1APPSNCA | |
| SCHEMBL22823111 | 0.69 | CASP3 (0.59) | METAP1MAPTALDH1A1APPLMNA | |
| SCHEMBL3093347 | 0.68 | ALDH1A1 (0.59) | METAP1TDP1MAPTALDH1A1APP | |
| SCHEMBL9287352 | 0.68 | MAPT (0.62) | METAP1MAPTALDH1A1APPSNCA | |
| SCHEMBL27855209 | 0.68 | HSD17B10 (0.64) | TDP1MAPTALDH1A1L3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4389477-A | Photoconductive composition sensitized by a thiobarbituric acid derivative | FUJI PHOTO FILM CO., LTD. (JP) | 1983-06-21 | — | — | US | disclosed |