Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.51 |
| ▸ | APP | P05067 | 3/20 | 0.51 |
| ▸ | SNCA | P37840 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.49 |
| ▸ | TNFRSF1A | P19438 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | POLB | P06746 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | METAP1 | P53582 | 1/20 | 0.49 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11147292 | 0.90 | MAPT (0.50) | MAPTAPPSNCAALDH1A1KMT2A | |
| SCHEMBL11146842 | 0.84 | NR1H4 (0.60) | MAPTALDH1A1KMT2ATNFRSF1AMEN1 | |
| SCHEMBL11148683 | 0.81 | METAP1 (0.53) | MAPTAPPSNCAALDH1A1KMT2A | |
| SCHEMBL11147680 | 0.80 | TNFRSF1A (0.44) | MAPTALDH1A1KMT2ATNFRSF1AMEN1 | |
| SCHEMBL11148687 | 0.79 | TNFRSF1A (0.60) | MAPTALDH1A1KMT2ATNFRSF1AMEN1 | |
| SCHEMBL11142094 | 0.79 | MEN1 (0.54) | MAPTALDH1A1KMT2ATNFRSF1AMEN1 | |
| SCHEMBL11149658 | 0.79 | TNFRSF1A (0.56) | MAPTALDH1A1KMT2ATNFRSF1AMEN1 | |
| SCHEMBL11149380 | 0.77 | METAP1 (0.49) | MAPTAPPSNCAALDH1A1KMT2A | |
| SCHEMBL11146884 | 0.77 | MAPT (0.51) | MAPTALDH1A1KMT2ATNFRSF1AMEN1 | |
| SCHEMBL11281995 | 0.76 | ALDH1A1 (0.52) | MAPTALDH1A1KMT2APOLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4389477-A | Photoconductive composition sensitized by a thiobarbituric acid derivative | FUJI PHOTO FILM CO., LTD. (JP) | 1983-06-21 | — | — | US | claimed |
| US-4389477-A | Photoconductive composition sensitized by a thiobarbituric acid derivative | FUJI PHOTO FILM CO., LTD. (JP) | 1983-06-21 | — | — | US | disclosed |