Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CKS1B | P61024 | 2/20 | 0.49 |
| ▸ | SKP1 | P63208 | 2/20 | 0.49 |
| ▸ | SKP2 | Q13309 | 2/20 | 0.49 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | ACACB | O00763 | 4/20 | 0.44 |
| ▸ | DRD2 | P14416 | 3/20 | 0.43 |
| ▸ | DRD3 | P35462 | 3/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | HPGDS | O60760 | 1/20 | 0.42 |
| ▸ | SMO | Q99835 | 1/20 | 0.41 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.40 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.40 |
| ▸ | ITGAL | P20701 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11144665 | 0.83 | HRH3 (0.54) | CKS1BSKP1SKP2ACACBDRD3 | |
| SCHEMBL11152253 | 0.79 | TSHR (0.52) | CKS1BSKP1SKP2FFAR4C5AR1 | |
| SCHEMBL31264582 | 0.78 | ALDH1A1 (0.45) | FFAR4C5AR1 | |
| SCHEMBL11148822 | 0.77 | CKS1B (0.57) | CKS1BSKP1SKP2ACACBDRD3 | |
| SCHEMBL25233477 | 0.77 | CKS1B (0.47) | CKS1BSKP1SKP2ACACB | |
| SCHEMBL28601568 | 0.76 | MAP4K4 (0.59) | CKS1BSKP1SKP2ITGB2ICAM1 | |
| SCHEMBL28601566 | 0.76 | MAP4K4 (0.59) | CKS1BSKP1SKP2ITGB2ICAM1 | |
| SCHEMBL28805208 | 0.76 | KDM4E (0.44) | FFAR4HTR1AHSD11B1 | |
| SCHEMBL11152923 | 0.75 | CKS1B (0.55) | CKS1BSKP1SKP2ACACBSMO | |
| SCHEMBL11148903 | 0.75 | HTR3E (0.57) | CKS1BSKP1SKP2CNR1SMO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4409228-A | ANOREXIGENIC AGENTS | SANOFI (FR) | 1983-10-11 | — | — | US | disclosed |
| EP-0021973-B1 | ANORECTIC AMINO PIPERIDINES, PROCESS FOR THEIR PREPARATION AND MEDICAMENTS CONTAINING THEM | SANOFI S.A. (FR) | 1982-12-08 | — | — | EP | disclosed |
| EP-0021973-A2 | Anorectic amino piperidines, process for their preparation and medicaments containing them | SANOFI S.A. (FR) | 1981-01-07 | — | — | EP | disclosed |