Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | PHGDH | O43175 | 1/20 | 0.32 |
| ▸ | MGLL | Q99685 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 4/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11149498 | 0.81 | KMT2A (0.35) | KMT2AHTTMEN1NPSR1FAAH | |
| SCHEMBL11151428 | 0.80 | KMT2A (0.35) | KMT2AHTTMEN1POLB | |
| SCHEMBL7078980 | 0.79 | HTT (0.43) | KMT2AHTTMEN1NPSR1ALDH1A1 | |
| SCHEMBL11155634 | 0.76 | NR1I2 (0.37) | KMT2AHTTMEN1NPSR1ALDH1A1 | |
| SCHEMBL11501967 | 0.76 | ALDH1A1 (0.41) | KMT2AHTTMEN1NPSR1FAAH | |
| SCHEMBL11150357 | 0.74 | SMN1; SMN2 (0.34) | KMT2AHTTMEN1NPSR1ALDH1A1 | |
| SCHEMBL11155465 | 0.72 | RAB9A (0.36) | KMT2AHTTMEN1NPSR1ALDH1A1 | |
| SCHEMBL11154367 | 0.72 | LMNA (0.36) | KMT2AMEN1ALDH1A1TSHRRAB9A | |
| SCHEMBL6686855 | 0.72 | HTT (0.43) | KMT2AHTTMEN1NPSR1ALDH1A1 | |
| SCHEMBL11149509 | 0.70 | PPIB (0.31) | KMT2AHTTMEN1NPSR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4405796-A | Processes for making phosphorus derivatives of aminothiomethylcarbamates | THE UPJOHN COMPANY (US) | 1983-09-20 | — | — | US | disclosed |
| US-4354975-A | Processes for making phosphorus derivatives of aminothiomethylcarbamates | THE UPJOHN COMPANY (US) | 1982-10-19 | — | — | US | disclosed |
| US-4279840-A | Processes for making phosphorus containing aminothiocarbamoyl halides | THE UPJOHN COMPANY (US) | 1981-07-21 | — | — | US | disclosed |
| US-4279839-A | Processes for making phosphorus containing aminothiocarbamoyl halides | THE UPJOHN COMPANY (US) | 1981-07-21 | — | — | US | disclosed |
| US-4234521-A | Phosphorus derivatives of aminothiocarbamoyl halides | THE UPJOHN COMPANY (US) | 1980-11-18 | — | — | US | disclosed |