Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11416195 | 0.80 | MEN1 (0.34) | LMNAACHEMEN1KMT2ATSHR | |
| SCHEMBL11155634 | 0.80 | NR1I2 (0.37) | LMNAACHEMEN1KMT2ATSHR | |
| SCHEMBL11149498 | 0.77 | KMT2A (0.35) | LMNAACHEMEN1KMT2ATSHR | |
| SCHEMBL11155465 | 0.76 | RAB9A (0.36) | ACHEMEN1KMT2ATSHRALDH1A1 | |
| SCHEMBL11438608 | 0.76 | LMNA (0.40) | LMNAACHEMEN1KMT2ATSHR | |
| SCHEMBL11158581 | 0.74 | POLB (0.33) | MEN1KMT2AALDH1A1 | |
| SCHEMBL11159437 | 0.73 | L3MBTL1 (0.38) | LMNAACHEMEN1KMT2ATSHR | |
| SCHEMBL11150357 | 0.72 | SMN1; SMN2 (0.34) | LMNAACHEMEN1KMT2AALDH1A1 | |
| SCHEMBL11149504 | 0.72 | KMT2A (0.39) | MEN1KMT2ATSHRALDH1A1NPC1 | |
| SCHEMBL11150155 | 0.71 | MEN1 (0.35) | LMNAMEN1KMT2AALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4234521-A | Phosphorus derivatives of aminothiocarbamoyl halides | THE UPJOHN COMPANY (US) | 1980-11-18 | — | — | US | claimed |
| US-4405796-A | Processes for making phosphorus derivatives of aminothiomethylcarbamates | THE UPJOHN COMPANY (US) | 1983-09-20 | — | — | US | disclosed |
| US-4354975-A | Processes for making phosphorus derivatives of aminothiomethylcarbamates | THE UPJOHN COMPANY (US) | 1982-10-19 | — | — | US | disclosed |
| US-4336207-A | Phosphorus derivatives of aminothiocarbamoyl halides | THE UPJOHN COMPANY (US) | 1982-06-22 | — | — | US | disclosed |
| US-4279840-A | Processes for making phosphorus containing aminothiocarbamoyl halides | THE UPJOHN COMPANY (US) | 1981-07-21 | — | — | US | disclosed |
| US-4279839-A | Processes for making phosphorus containing aminothiocarbamoyl halides | THE UPJOHN COMPANY (US) | 1981-07-21 | — | — | US | disclosed |
| US-4234521-A | Phosphorus derivatives of aminothiocarbamoyl halides | THE UPJOHN COMPANY (US) | 1980-11-18 | — | — | US | disclosed |