SCHEMBL11149656

SCHEMBL11149656

O=C1Cc2cc(Cl)c(NC(C3CC3)C3CC3)cc2O1

nearest known ligand 0.50

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.30
MAOB P27338 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10950235 0.73 ADRA2A (0.30)
SCHEMBL13283638 0.67 MAOA (0.42) MAOAMAOB
Clofurac SCHEMBL2108737 0.67 CEL (0.40)
SCHEMBL11390374 0.63 MAOA (0.43) MAOAMAOB
SCHEMBL10987551 0.61 ALDH1A1 (0.41)
SCHEMBL6287157 0.60 MAOA (0.54) MAOAMAOB
SCHEMBL29114213 0.60 CA12 (0.47) MAOAMAOB
SCHEMBL29642661 0.60 MAOA (0.54) MAOAMAOB
SCHEMBL32672782 0.59 MAOA (0.37) MAOAMAOB
SCHEMBL14030771 0.59 MAOB (0.37) MAOAMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0078240-A2 Lactones CIBA-GEIGY AG (CH) 1983-05-04 EP disclosed