SCHEMBL11149740

SCHEMBL11149740

CC(C)(c1cccc2ccccc12)S(=O)(=O)O

nearest known ligand 0.44

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
CA9 Q16790 1/20 0.44
F2 P00734 3/20 0.41
PRSS1 P07477 3/20 0.41
PRSS2 P07478 3/20 0.41
PRSS3 P35030 3/20 0.41
KEAP1 Q14145 1/20 0.41
HCRTR1 O43613 1/20 0.41
ACP3 P15309 1/20 0.41
ALDH1A1 P00352 2/20 0.40
KDM4E B2RXH2 2/20 0.40
HSD17B10 Q99714 1/20 0.40
KIF11 P52732 1/20 0.38
HTR6 P50406 2/20 0.38
CYP1A2 P05177 1/20 0.38
CYP2A6 P11509 1/20 0.38
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29763080 0.85 KEAP1 (0.43) CA1CA2CA9F2PRSS1
SCHEMBL35772 0.85 KEAP1 (0.43) CA1CA2CA9F2PRSS1
SCHEMBL11606350 0.83 KEAP1 (0.42) CA1CA2CA9F2PRSS1
SCHEMBL1719758 0.83 KEAP1 (0.42) CA1CA2CA9F2PRSS1
SCHEMBL11651931 0.83 KEAP1 (0.42) CA1CA2CA9F2PRSS1
Benzene SCHEMBL27652672 0.81 ACP3 (0.44) CA1CA2CA9F2PRSS1
SCHEMBL3871886 0.78 MEN1 (0.44) CA1CA2CA9F2PRSS1
SCHEMBL28443456 0.77 KIF11 (0.39) CA1CA2CA9F2PRSS1
SCHEMBL3876388 0.76 KDM4E (0.43) CA1CA2CA9F2PRSS1
SCHEMBL11326993 0.75 KIF11 (0.46) CA1CA2CA9F2PRSS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4422854-A Transfer printing support, process for the manufacture thereof, with blue azo dye:di-cyano-nitro-phenyl-azo aniline HOECHST AKTIENGESELLSCHAFT (DE) 1983-12-27 US disclosed