Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | CASP1 | P29466 | 2/20 | 0.40 |
| ▸ | CASP7 | P55210 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LIMK1 | P53667 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | OGG1 | O15527 | 1/20 | 0.36 |
| ▸ | TYK2 | P29597 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11148719 | 0.83 | KDM4E (0.43) | MAPTKDM4ECASP1CASP7HSD17B10 | |
| SCHEMBL11150491 | 0.77 | HSD17B10 (0.41) | MAPTKDM4ECASP1CASP7HSD17B10 | |
| SCHEMBL16006510 | 0.73 | KDM4E (0.45) | MAPTKDM4ECASP1CASP7HSD17B10 | |
| SCHEMBL17697553 | 0.72 | CASP1 (0.40) | MAPTKDM4ECASP1CASP7HSD17B10 | |
| SCHEMBL11151333 | 0.71 | MAPT (0.39) | MAPTKDM4EHSD17B10ALDH1A1POLB | |
| SCHEMBL19788774 | 0.71 | CASP1 (0.38) | MAPTKDM4ECASP1CASP7HSD17B10 | |
| SCHEMBL11149542 | 0.67 | PARP14 (0.47) | MAPTKDM4ECASP1CASP7HSD17B10 | |
| SCHEMBL17621512 | 0.66 | CASP1 (0.34) | MAPTKDM4ECASP1CASP7HSD17B10 | |
| SCHEMBL16006485 | 0.65 | MAPT (0.37) | MAPTKDM4ECASP1CASP7HSD17B10 | |
| SCHEMBL16006561 | 0.65 | MAPT (0.37) | MAPTKDM4ECASP1CASP7HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0005357-B1 | N-(BENZOTHIENOPYRAZOL)-AMIDES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1983-02-09 | — | — | EP | disclosed |
| EP-0005357-A1 | N-(Benzothienopyrazol)-amides and pharmaceutical compositions containing them | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1979-11-14 | — | — | EP | disclosed |
| US-4140785-A | N-(benzothienopyrazol)amide antirhinoviral agents | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1979-02-20 | — | — | US | disclosed |