SCHEMBL11150910

SCHEMBL11150910

CCN(CC)c1ccc(NS(=O)(=O)c2ccc(C)cc2)c(C)c1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.65
POLB P06746 4/20 0.65
TP53 P04637 3/20 0.65
LMNA P02545 3/20 0.65
GAA P10253 5/20 0.60
GFER P55789 4/20 0.60
ALDH1A1 P00352 4/20 0.60
HPGD P15428 2/20 0.60
KDM4E B2RXH2 1/20 0.60
ALOX15 P16050 1/20 0.60
MAPK1 P28482 1/20 0.60
HSD17B10 Q99714 1/20 0.60
CNR2 P34972 1/20 0.56
FFAR4 Q5NUL3 2/20 0.53
HTT P42858 2/20 0.52
NPSR1 Q6W5P4 1/20 0.52
KEAP1 Q14145 1/20 0.50
NFE2L2 Q16236 1/20 0.50
GRK2 P25098 1/20 0.49
DNMT1 P26358 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13650238 0.90 MAPT (0.54) MAPTPOLBTP53LMNAGAA
SCHEMBL8438245 0.82 ALDH1A1 (0.57) MAPTPOLBTP53LMNAGAA
SCHEMBL9641572 0.81 MAPT (0.55) MAPTPOLBTP53LMNAGAA
SCHEMBL29048726 0.80 FFAR4 (0.77) MAPTTP53LMNAGAAGFER
SCHEMBL8930956 0.80 ALDH1A1 (0.72) MAPTLMNAGAAGFERALDH1A1
SCHEMBL9555083 0.80 MAPT (0.56) MAPTPOLBTP53LMNAGAA
SCHEMBL10827874 0.80 MAPT (0.63) MAPTPOLBTP53LMNAGAA
SCHEMBL10955266 0.79 KEAP1 (0.52) MAPTPOLBTP53LMNAGAA
SCHEMBL13852947 0.78 NPC1 (0.58) MAPTPOLBLMNAGAAGFER
SCHEMBL10827842 0.78 GFER (0.53) MAPTPOLBTP53LMNAGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4373017-A YELLOW, MAGENTA, AND CYAN-COLORED COMPOUNDS FROM ULTRA-VIOLET-IRRADIATED LEUCO DYES; PRINTING PLATES KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1983-02-08 US disclosed
EP-0035262-A2 Photosensitive material especially photosensitive presensitized printing plate and leuco-dyes contained therein KONICA CORPORATION (JP) 1981-09-09 EP disclosed