SCHEMBL8438245

SCHEMBL8438245

CCN(CC)c1ccc(NC(=O)NS(=O)(=O)c2ccc(C)cc2)c(C)c1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.57
LMNA P02545 4/20 0.57
TSHR P16473 1/20 0.57
POLB P06746 2/20 0.54
GRK2 P25098 1/20 0.54
DNMT1 P26358 1/20 0.54
CTDSP1 Q9GZU7 1/20 0.54
PPARG P37231 1/20 0.54
RAB9A P51151 1/20 0.54
RXFP1 Q9HBX9 1/20 0.54
NR2E3 Q9Y5X4 1/20 0.54
NCOR2 Q9Y618 1/20 0.54
L3MBTL1 Q9Y468 1/20 0.54
MAPT P10636 7/20 0.52
GAA P10253 2/20 0.52
KDM4E B2RXH2 1/20 0.52
KMT2A Q03164 4/20 0.51
MEN1 O00255 3/20 0.50
TP53 P04637 2/20 0.50
THRB P10828 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14452020 0.82 MAPT (0.49) ALDH1A1LMNAPOLBGRK2DNMT1
SCHEMBL11150910 0.82 MAPT (0.65) ALDH1A1LMNAPOLBGRK2DNMT1
SCHEMBL6464678 0.81 LMNA (0.63) ALDH1A1LMNATSHRPPARGRAB9A
SCHEMBL6468156 0.80 ALDH1A1 (0.69) ALDH1A1LMNATSHRPPARGRAB9A
SCHEMBL6465678 0.80 ALDH1A1 (0.59) ALDH1A1LMNATSHRPPARGRAB9A
SCHEMBL24691473 0.80 KMT2A (0.62) ALDH1A1LMNATSHRPPARGRAB9A
SCHEMBL6466795 0.80 KMT2A (0.67) ALDH1A1LMNATSHRPPARGRAB9A
SCHEMBL2109657 0.79 CNR2 (0.49) ALDH1A1LMNATSHRPOLBGRK2
SCHEMBL13650238 0.78 MAPT (0.54) ALDH1A1LMNAPOLBGRK2DNMT1
SCHEMBL6466852 0.78 ALDH1A1 (0.66) ALDH1A1LMNATSHRPPARGRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2107122-A1 Protease detection material, set of protease detection materials, and method for measuring protease FUJIFILM Corporation (JP) 2009-10-07 EP disclosed
US-20090246815-A1 PROTEASE DETECTION MATERIAL, SET OF PROTEASE DETECTION MATERIALS, AND METHOD FOR MEASURING PROTEASE FUJIFILM CORPORATION (JP) 2009-10-01 US disclosed
US-20090246815-A1 PROTEASE DETECTION MATERIAL, SET OF PROTEASE DETECTION MATERIALS, AND METHOD FOR MEASURING PROTEASE FUJIFILM CORPORATION (JP) 2009-10-01 US disclosed
US-7250249-B2 Black and white photothermographic material FUJIFILM CORPORATION (JP) 2007-07-31 US disclosed
US-7250249-B2 Black and white photothermographic material FUJIFILM CORPORATION (JP) 2007-07-31 US disclosed
US-7247421-B2 Image forming method using photothermographic material FUJIFILM CORPORATION (JP) 2007-07-24 US disclosed
US-7247421-B2 Image forming method using photothermographic material FUJIFILM CORPORATION (JP) 2007-07-24 US disclosed
US-5885788-A CONDUCTING THE MEASUREMENT OF CHOLESTEROL IN THE PRESENCE OF AN AMPHOTERIC SURFACTANT AND AN ALIPHATIC AMINE CONTAINING CARBOXYL GROUPS(S) OR SULFONIC ACID GROUP(S) WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 1999-03-23 US disclosed
EP-0821239-A2 Method for measuring an amount of LDL-cholesterol WAKO PURE CHEMICAL INDUSTRIES, LTD (JP) 1998-01-28 EP disclosed