Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PCNA | P12004 | 14/20 | 0.47 |
| ▸ | LIG1 | P18858 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 4/20 | 0.38 |
| ▸ | THRA | P10827 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4926016 | 0.85 | PCNA (0.52) | PCNALIG1THRBTHRALMNA | |
| SCHEMBL1115191 | 0.85 | PCNA (0.52) | PCNALIG1THRBTHRALMNA | |
| SCHEMBL11226810 | 0.80 | PCNA (0.47) | PCNALIG1THRBTHRALMNA | |
| SCHEMBL9222347 | 0.79 | PCNA (0.44) | PCNALMNACYP2D6TSHR | |
| SCHEMBL31368013 | 0.78 | PCNA (0.71) | PCNALIG1THRBTHRALMNA | |
| SCHEMBL34943 | 0.78 | PCNA (0.71) | PCNALIG1THRBTHRALMNA | |
| SCHEMBL2679290 | 0.78 | PCNA (0.70) | PCNALIG1THRBTHRALMNA | |
| SCHEMBL5501440 | 0.78 | PCNA (0.70) | PCNALIG1THRBTHRALMNA | |
| Sulfuric Acid SCHEMBL2513306 | 0.76 | PCNA (0.67) | PCNALIG1THRBTHRALMNA | |
| SCHEMBL7596233 | 0.73 | PCNA (0.66) | PCNALIG1THRBTHRALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5500807-A | Selection method for pharmacologically active compounds | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1996-03-19 | — | — | US | disclosed |
| WO-1990007329-A1 | SELECTION METHOD FOR PHARMACOLOGICALLY ACTIVE COMPOUNDS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1990-07-12 | — | — | WO | disclosed |