Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PCNA | P12004 | 14/20 | 0.47 |
| ▸ | ACE | P12821 | 1/20 | 0.39 |
| ▸ | LIG1 | P18858 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 4/20 | 0.36 |
| ▸ | THRA | P10827 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GABRP | O00591 | 1/20 | 0.36 |
| ▸ | GABRD | O14764 | 1/20 | 0.36 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.36 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1115191 | 0.85 | PCNA (0.52) | PCNALIG1THRBTHRALMNA | |
| SCHEMBL4926016 | 0.85 | PCNA (0.52) | PCNALIG1THRBTHRALMNA | |
| SCHEMBL9222347 | 0.80 | PCNA (0.44) | PCNALMNACYP2D6TSHR | |
| SCHEMBL8988780 | 0.80 | PCNA (0.47) | PCNALIG1THRBTHRALMNA | |
| SCHEMBL34943 | 0.78 | PCNA (0.71) | PCNALIG1THRBTHRALMNA | |
| SCHEMBL31368013 | 0.78 | PCNA (0.71) | PCNALIG1THRBTHRALMNA | |
| SCHEMBL5501440 | 0.77 | PCNA (0.70) | PCNALIG1THRBTHRALMNA | |
| SCHEMBL2679290 | 0.77 | PCNA (0.70) | PCNALIG1THRBTHRALMNA | |
| Sulfuric Acid SCHEMBL2513306 | 0.75 | PCNA (0.67) | PCNALIG1THRBTHRALMNA | |
| SCHEMBL8047744 | 0.74 | THRB (0.60) | PCNATHRBTHRALMNACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4332784-A | SELENIUM USED IN THYROID RADIOIMMUNOASSAY | THE RADIOCHEMICAL CENTRE LIMITED (GB) | 1982-06-01 | — | — | US | disclosed |
| US-4311853-A | Selenium derivatives of thyroxine and tri-iodothyronine | THE RADIOCHEMICAL CENTRE LIMITED (GB) | 1982-01-19 | — | — | US | disclosed |