Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.46 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.42 |
| ▸ | MAPT | P10636 | 9/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 5/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | GFER | P55789 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5771929 | 0.81 | NR4A2 (0.42) | MEN1KMT2ANR4A2ALDH1A1KDM4E | |
| SCHEMBL5768460 | 0.80 | PFKFB1 (0.41) | MEN1KMT2ANR4A2ALDH1A1KDM4E | |
| SCHEMBL10462854 | 0.77 | KDM4E (0.57) | MEN1KMT2ANR4A2ALDH1A1KDM4E | |
| SCHEMBL9573828 | 0.75 | GABRA1 (0.47) | MEN1KMT2ANR4A2ALDH1A1KDM4E | |
| SCHEMBL9573773 | 0.75 | HPGD (0.49) | MEN1KMT2AALDH1A1KDM4EMAPT | |
| SCHEMBL9573800 | 0.75 | TUBB4A (0.51) | MEN1KMT2AALDH1A1MAPTHPGD | |
| SCHEMBL6291860 | 0.75 | MEN1 (0.60) | MEN1KMT2AALDH1A1KDM4EMAPT | |
| SCHEMBL8809770 | 0.73 | NR4A2 (0.49) | MEN1KMT2ANR4A2ALDH1A1KDM4E | |
| SCHEMBL31081242 | 0.72 | HPGD (0.42) | NR4A2KDM4EMAPTHPGDHSD17B10 | |
| SCHEMBL31081033 | 0.72 | HPGD (0.42) | NR4A2KDM4EMAPTHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0071935-A2 | 1-Phenyl-2-aminocarbonylindole compounds, process and intermediates for their preparation and medicines containing them | Kali-Chemie Pharma GmbH (DE) | 1983-02-16 | — | — | EP | disclosed |