Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | DGKA | P23743 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | TOP2A | P11388 | 1/20 | 0.30 |
| ▸ | NAAA | Q02083 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1115574 | 0.91 | TSHR (0.45) | TSHRDGKAMAPTHTR2CMGLL | |
| SCHEMBL8586144 | 0.84 | ALDH1A1 (0.31) | ALDH1A1LMNA | |
| SCHEMBL20741927 | 0.79 | TSHR (0.56) | TSHRDGKAMAPTALDH1A1DNM1 | |
| SCHEMBL27208999 | 0.78 | EGLN1 (0.35) | TSHRMAPTBLMLMNA | |
| SCHEMBL8911328 | 0.78 | — | — | |
| SCHEMBL28595272 | 0.75 | BBOX1 (0.32) | — | |
| SCHEMBL20589 | 0.74 | DGKA (0.58) | TSHRDGKAADRA2AADRA1AMAPT | |
| SCHEMBL515043 | 0.73 | TSHR (0.47) | TSHRDGKAADRA2AADRA1AMAPT | |
| SCHEMBL11363845 | 0.71 | — | — | |
| SCHEMBL514827 | 0.70 | TSHR (0.53) | TSHRDGKAMAPTHTR2CMGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1744222-B1 | Toner, developer, image forming method, and toner container | RICOH CO LTD (JP) | 2011-02-02 | — | — | EP | disclosed |
| US-7629099-B2 | Toner, developer, image forming method, and toner container | RICOH COMPANY LIMITED (JP) | 2009-12-08 | — | — | US | disclosed |
| US-20070015077-A1 | Toner, developer, image forming method, and toner container | RICOH COMPANY LIMITED (JP) | 2007-01-18 | — | — | US | disclosed |
| EP-1744222-A2 | Toner, developer, image forming method, and toner container | Ricoh Company, Ltd. (JP) | 2007-01-17 | — | — | EP | disclosed |