Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.53 |
| ▸ | DGKA | P23743 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | MGLL | Q99685 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.43 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.42 |
| ▸ | PGR | P06401 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | PAM | P19021 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL515243 | 0.94 | ALDH1A1 (0.59) | TSHRDGKAALDH1A1LMNAMGLL | |
| SCHEMBL15758052 | 0.93 | ALDH1A1 (0.62) | TSHRDGKAALDH1A1LMNAMGLL | |
| SCHEMBL514908 | 0.93 | ALDH1A1 (0.62) | TSHRDGKAALDH1A1LMNAMGLL | |
| SCHEMBL514724 | 0.93 | ALDH1A1 (0.62) | TSHRDGKAALDH1A1LMNAMGLL | |
| SCHEMBL6434039 | 0.93 | ALDH1A1 (0.62) | TSHRDGKAALDH1A1LMNAMGLL | |
| SCHEMBL3694489 | 0.93 | ALDH1A1 (0.62) | TSHRDGKAALDH1A1LMNAMGLL | |
| SCHEMBL513683 | 0.91 | TSHR (0.56) | TSHRDGKAALDH1A1LMNAMGLL | |
| SCHEMBL3117539 | 0.89 | TSHR (0.59) | TSHRDGKAALDH1A1LMNAMGLL | |
| SCHEMBL515043 | 0.88 | TSHR (0.47) | TSHRDGKAALDH1A1LMNAMGLL | |
| SCHEMBL25397233 | 0.87 | TSHR (0.62) | TSHRDGKAALDH1A1LMNAMGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116082157-A | Method for preparing organic carboxylic ester by olefine unsaturated compound alkoxycarbonyl reaction | 上海梓龄化工技术有限公司 | 2023-05-09 | — | — | CN | claimed |
| CN-107323055-A | TPU film for automobile surface protection and preparation method of self-repairing coating thereof | 东莞市鼎力薄膜科技有限公司 | 2017-11-07 | — | — | CN | claimed |
| CN-116082157-A | Method for preparing organic carboxylic ester by olefine unsaturated compound alkoxycarbonyl reaction | 上海梓龄化工技术有限公司 | 2023-05-09 | — | — | CN | disclosed |
| CN-107323055-A | TPU film for automobile surface protection and preparation method of self-repairing coating thereof | 东莞市鼎力薄膜科技有限公司 | 2017-11-07 | — | — | CN | disclosed |
| US-9714271-B2 | Cyclosporine analogue molecules modified at amino acid 1 and 3 | CONTRAVIR PHARMACEUTICALS, INC. (US) | 2017-07-25 | — | — | US | disclosed |
| US-20160207961-A1 | Cyclosporine Analogue Molecules Modified At Amino Acid 1 and 3 | ACHILLE LIFE SCIENCES LIMITED (GB) | 2016-07-21 | — | — | US | disclosed |
| US-9200038-B2 | Cyclosporine analogue molecules modified at amino acid 1 and 3 | CICLOFILIN PHARMACEUTICALS CORP. (CA) | 2015-12-01 | — | — | US | disclosed |
| CN-102369173-B | Method for producing high-purity terminal olefin compound | KURARAY CO | 2014-09-10 | — | — | CN | disclosed |
| US-20140142033-A1 | CYCLOSPORINE ANALOGUE MOLECULES MODIFIED AT AMINO ACID 1 AND 3 | ISOTECHNIKA PHARMA INC. (CA) | 2014-05-22 | — | — | US | disclosed |
| EP-2415740-B1 | METHOD FOR PRODUCING HIGH-PURITY TERMINAL OLEFIN COMPOUND | KURARAY CO (JP) | 2013-12-25 | — | — | EP | disclosed |
| US-8609886-B2 | Method for producing high purity terminal olefin compound | KURARAY CO., LTD. (JP) | 2013-12-17 | — | — | US | disclosed |
| US-20130190223-A1 | NONIMMUNOSUPPRESSIVE CYCLOSPORINE ANALOGUE MOLECULES | ISOTECHNIKA PHARMA INC. (CA) | 2013-07-25 | — | — | US | disclosed |
| CN-102369173-A | Method for producing high-purity terminal olefin compound | KURARAY CO | 2012-03-07 | — | — | CN | disclosed |
| EP-2415740-A1 | METHOD FOR PRODUCING HIGH-PURITY TERMINAL OLEFIN COMPOUND | Kuraray Co., Ltd. (JP) | 2012-02-08 | — | — | EP | disclosed |
| US-20120029229-A1 | METHOD FOR PRODUCING HIGH PURITY TERMINAL OLEFIN COMPOUND | KURARAY CO., LTD. (JP) | 2012-02-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130190223-A1 | NONIMMUNOSUPPRESSIVE CYCLOSPORINE ANALOGUE MOLECULES | CD40, FKBP1A, FKBP4 | TSHR 2593/4885DGKA 3357/4885ALDH1A1 2494/4885 |
| US-20160207961-A1 | Cyclosporine Analogue Molecules Modified At Amino Acid 1 and 3 | FKBP1A, CHP1, FKBP3 | TSHR 4502/4885DGKA 3680/4885ALDH1A1 3240/4885 |
| US-20140142033-A1 | CYCLOSPORINE ANALOGUE MOLECULES MODIFIED AT AMINO ACID 1 AND 3 | FKBP1A, CHP1, FKBP3 | TSHR 4502/4885DGKA 3680/4885ALDH1A1 3240/4885 |
| US-20120029229-A1 | METHOD FOR PRODUCING HIGH PURITY TERMINAL OLEFIN COMPOUND | ADH1A, ADH1C, OSBP | TSHR 3218/4885DGKA 545/4885ALDH1A1 233/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.