SCHEMBL111553

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL111081	0.91	ALDH1A1 (0.58)	PKMTDP1RAB9AKMT2AALDH1A1
	SCHEMBL114090	0.90	KMT2A (0.56)	RAB9AKMT2APOLBLMNAMAPT
	SCHEMBL110852	0.90	KMT2A (0.59)	RAB9AKMT2APOLBLMNAMAPT
	SCHEMBL115046	0.89	LMNA (0.58)	RAB9AKMT2APOLBLMNAMAPT
	SCHEMBL112248	0.89	RAB9A (0.46)	PKMTDP1RAB9AKMT2APOLB
	SCHEMBL113246	0.88	GAA (0.52)	RAB9APOLBLMNAMAPTBRAF
	SCHEMBL112384	0.87	GAA (0.52)	RAB9APOLBLMNAMAPTKDM4E
	SCHEMBL111258	0.87	LMNA (0.51)	RAB9APOLBLMNAMAPTKDM4E
	SCHEMBL111089	0.85	POLB (0.63)	TDP1RAB9APOLBMAPTKDM4E
	SCHEMBL13076824	0.83	NAMPT (0.52)	TDP1KMT2AKDM4EALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.