Known targets — ChEMBL curated mechanism
ACEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ATP4AATP4BAXLBTKCACNA1CCACNA1DCACNA1FCACNA1SCCR5CHRM2CHRM3CPT1BCPT2DPP4DRD1DRD2EGFRERBB2ERBB4FLT3HRH1HRH3HTR1AHTR2AHTR2BHTR2CHTR4JAK1JAK2JAK3KCNH2KMT2AMAP2K1MAP2K2MEN1MLNRMPLMTORPPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PLK4PPARGRENS1PR1SLC6A2SLC6A3SLC6A4SMOTYK2atpAatpBatpCatpDatpEatpFatpFHatpGpol
The experimentally established mechanism targets of Tetrylammonium. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BBOX1 | O75936 | 4/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | KCNA1 | Q09470 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tetrylammonium SCHEMBL3864261 | 1.00 | BBOX1 (0.44) | BBOX1TSHRNFKB1KCNA1KDM4E | |
| Tetrylammonium SCHEMBL2452722 | 0.97 | BBOX1 (0.46) | BBOX1TSHRNFKB1KCNA1KDM4E | |
| Tetrylammonium SCHEMBL2353697 | 0.97 | BBOX1 (0.46) | BBOX1TSHRNFKB1KCNA1KDM4E | |
| Tetrylammonium SCHEMBL2348762 | 0.97 | BBOX1 (0.46) | BBOX1TSHRNFKB1KCNA1KDM4E | |
| Tetrylammonium SCHEMBL2346208 | 0.95 | BBOX1 (0.44) | BBOX1TSHRNFKB1KCNA1KDM4E | |
| Tetrylammonium SCHEMBL2351931 | 0.95 | BBOX1 (0.44) | BBOX1TSHRNFKB1KCNA1KDM4E | |
| Tetrylammonium SCHEMBL2346200 | 0.95 | BBOX1 (0.44) | BBOX1TSHRNFKB1KCNA1KDM4E | |
| Tetrylammonium SCHEMBL2452720 | 0.88 | TSHR (0.41) | BBOX1TSHRNFKB1KCNA1KDM4E | |
| Tetrylammonium SCHEMBL2351488 | 0.88 | TSHR (0.41) | BBOX1TSHRNFKB1KCNA1KDM4E | |
| Tetrylammonium SCHEMBL2349569 | 0.88 | TSHR (0.41) | BBOX1TSHRNFKB1KCNA1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4377692-A | ELECTROLYTE SOLUTES | SPRAGUE ELECTRIC COMPANY (US) | 1983-03-22 | — | — | US | disclosed |