Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | TTR | P02766 | 2/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.37 |
| ▸ | AKR1C1 | Q04828 | 3/20 | 0.37 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | CA2 | P00918 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9477739 | 0.77 | HSD17B10 (0.43) | HSD17B10CYP1A2CYP2C9CYP2C19HIF1A | |
| SCHEMBL11164010 | 0.72 | BLM (0.55) | HSD17B10SMN1; SMN2CYP1A2ALOX15HIF1A | |
| SCHEMBL4837077 | 0.72 | TSHR (0.47) | SMN1; SMN2AKR1C2AKR1C3ALDH1A1LMNA | |
| SCHEMBL15631294 | 0.71 | GABRA1 (0.59) | HSD17B10SMN1; SMN2CYP1A2CYP2C9ALOX15 | |
| SCHEMBL11528672 | 0.69 | HSD17B10 (0.54) | HSD17B10SMN1; SMN2CYP1A2CYP2C9ALOX15 | |
| SCHEMBL19426112 | 0.68 | CYP1A2 (0.38) | HSD17B10SMN1; SMN2CYP1A2CYP2C9ALOX15 | |
| SCHEMBL8150631 | 0.68 | GLRA3 (0.48) | HSD17B10SMN1; SMN2CYP1A2ALOX15ALOX12 | |
| SCHEMBL10441312 | 0.67 | CES2 (0.45) | LMNACA1CA12CA9NR1I2 | |
| SCHEMBL30689081 | 0.67 | TTR (0.78) | HSD17B10SMN1; SMN2TTRAKR1C2AKR1C1 | |
| SCHEMBL1458206 | 0.67 | TTR (0.78) | HSD17B10SMN1; SMN2TTRAKR1C2AKR1C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0091302-A1 | Beta-lactam derivatives | BEECHAM GROUP PLC (GB) | 1983-10-12 | — | — | EP | disclosed |