Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.45 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.44 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.44 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.44 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.44 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.44 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.44 |
| ▸ | APP | P05067 | 1/20 | 0.44 |
| ▸ | KMO | O15229 | 3/20 | 0.43 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9477739 | 0.84 | HSD17B10 (0.43) | TSHRAKR1C3AKR1C2ALDH1A1LMNA | |
| SCHEMBL6627440 | 0.82 | SLC6A3 (0.50) | TSHRAKR1C3AKR1C2ALDH1A1LMNA | |
| SCHEMBL2346696 | 0.79 | LMNA (0.50) | TSHRAKR1C3AKR1C2ALDH1A1LMNA | |
| SCHEMBL2346690 | 0.79 | LMNA (0.50) | TSHRAKR1C3AKR1C2ALDH1A1LMNA | |
| SCHEMBL11846789 | 0.78 | PTGS2 (0.45) | TSHRAKR1C3AKR1C2LMNAPSEN1 | |
| SCHEMBL7626560 | 0.78 | LMNA (0.49) | TSHRAKR1C3AKR1C2ALDH1A1LMNA | |
| SCHEMBL14661375 | 0.78 | VCAM1 (0.42) | ALDH1A1 | |
| SCHEMBL19554951 | 0.78 | HSD17B10 (0.56) | TSHRAKR1C3AKR1C2ALDH1A1LMNA | |
| SCHEMBL1512537 | 0.78 | AKR1C3 (0.69) | TSHRAKR1C3AKR1C2ALDH1A1LMNA | |
| SCHEMBL9298265 | 0.78 | TSHR (0.45) | TSHRAKR1C3AKR1C2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7442549-B2 | Method of constructing orchid haploid by treating unfertilized orchid flower with auxin and method of growing orchid | SAPPORO BREWERIES LIMITED (JP) | 2008-10-28 | — | — | US | claimed |
| US-20050289663-A1 | Method of constructing orchid haploid by treating unfertilized orchid flower with auxin and method of growing orchid | SAPPORO BREWERIES LIMITED (JP) | 2005-12-29 | — | — | US | claimed |
| EP-1541015-A1 | METHOD OF CONSTRUCTING ORCHID HAPLOID BY TREATING UNFERTILIZED OCRHID FLOWER WITH AUXIN AND METHOD OF GROWING ORCHID | Sapporo Breweries Limited (JP) | 2005-06-15 | — | — | EP | claimed |
| US-7442549-B2 | Method of constructing orchid haploid by treating unfertilized orchid flower with auxin and method of growing orchid | SAPPORO BREWERIES LIMITED (JP) | 2008-10-28 | — | — | US | disclosed |
| US-7256158-B2 | 2,4,5,-trisubstituted phenylketo-enols for use as pesticides and herbicides | BAYER AG (DE) | 2007-08-14 | — | — | US | disclosed |
| US-20050289663-A1 | Method of constructing orchid haploid by treating unfertilized orchid flower with auxin and method of growing orchid | SAPPORO BREWERIES LIMITED (JP) | 2005-12-29 | — | — | US | disclosed |
| US-6933261-B2 | 2,4,5-Trisubstituted phenylketoenols | BAYER AKTIENGESELLSCHAFT (DE) | 2005-08-23 | — | — | US | disclosed |
| EP-1541015-A1 | METHOD OF CONSTRUCTING ORCHID HAPLOID BY TREATING UNFERTILIZED OCRHID FLOWER WITH AUXIN AND METHOD OF GROWING ORCHID | Sapporo Breweries Limited (JP) | 2005-06-15 | — | — | EP | disclosed |
| US-20050038021-A1 | 2,4,5,-trisubstituted phenylketo-enols for use as pesticides and herbicides | BAYER AG (DE) | 2005-02-17 | — | — | US | disclosed |
| US-20030171219-A1 | 2,4,5-trisubstituted phenylketo-enols for use as pesticides and herbicides | LIEB FOLKER (DE) | 2003-09-11 | — | — | US | disclosed |
| US-6511942-B1 | Animal husbandry, veterinary medicine | BAYER AKTIENGESELLSCHAFT (DE) | 2003-01-28 | — | — | US | disclosed |
| US-6110872-A | 3-(2,4,5-TRISUBSTITUTED PHENYL), 4-HYDROXY,5,5-(CYCLOALKYL OR HETEROCYCLOALKYL)PYRROLIN-2-ONE AND DERIVATIVES; METHOD OF MAKING BY INTRAMOLECULAR CONDENSATION OF SPECIFIED COMPOUND | BAYER AKTIENGESELLSCHAFT (DE) | 2000-08-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050038021-A1 | 2,4,5,-trisubstituted phenylketo-enols for use as pesticides and herbicides | DDT, CYP4X1, PDHX | TSHR 2316/4885AKR1C3 40/4885AKR1C2 34/4885 |
| US-20030171219-A1 | 2,4,5-trisubstituted phenylketo-enols for use as pesticides and herbicides | DDT, CYP4X1, HPD | TSHR 2872/4885AKR1C3 41/4885AKR1C2 34/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.