Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | DPP4 | P27487 | 1/20 | 0.44 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | FEN1 | P39748 | 1/20 | 0.42 |
| ▸ | FABP3 | P05413 | 1/20 | 0.41 |
| ▸ | FABP4 | P15090 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27718440 | 0.80 | CA12 (0.48) | ALDH1A1KDM4ETSHRGAAMAPT | |
| SCHEMBL8479136 | 0.79 | GAA (0.42) | ALDH1A1DPP4PBRM1KDM4EHSD17B10 | |
| SCHEMBL80183 | 0.79 | ALDH1A1 (0.64) | ALDH1A1DPP4PBRM1KDM4EHSD17B10 | |
| SCHEMBL5317324 | 0.78 | ALDH1A1 (0.53) | ALDH1A1KDM4EHSD17B10TSHRGAA | |
| SCHEMBL8793059 | 0.78 | TDP1 (0.49) | ALDH1A1KDM4EHSD17B10TSHRGAA | |
| SCHEMBL4244111 | 0.77 | CES2 (0.48) | ALDH1A1KDM4ETSHRGAAMAPT | |
| SCHEMBL1041643 | 0.77 | ALDH1A1 (0.61) | ALDH1A1DPP4PBRM1KDM4EHSD17B10 | |
| SCHEMBL7425018 | 0.77 | ALDH1A1 (0.61) | ALDH1A1DPP4PBRM1KDM4EHSD17B10 | |
| Hydrochloric Acid SCHEMBL8042412 | 0.77 | ALDH1A1 (0.61) | ALDH1A1DPP4PBRM1KDM4EHSD17B10 | |
| SCHEMBL27697949 | 0.76 | CA12 (0.53) | ALDH1A1KDM4ETSHRGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0023569-B1 | DERIVATIVES OF CARBOXYLIC ACIDS, THEIR PREPARATION AND MEDICAMENTS CONTAINING THEM | Dr. Karl Thomae GmbH (DE) | 1983-06-22 | — | — | EP | disclosed |
| EP-0023569-A1 | Derivatives of carboxylic acids, their preparation and medicaments containing them | Dr. Karl Thomae GmbH (DE) | 1981-02-11 | — | — | EP | disclosed |