Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | FABP3 | P05413 | 2/20 | 0.38 |
| ▸ | FABP4 | P15090 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | FEN1 | P39748 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11157305 | 0.79 | ALDH1A1 (0.47) | GAAALDH1A1PBRM1DPP4KDM4E | |
| SCHEMBL9094620 | 0.74 | PBRM1 (0.41) | GAAALDH1A1PBRM1KDM4EHSD17B10 | |
| SCHEMBL1939814 | 0.73 | GAA (0.46) | GAAALDH1A1HSD17B10TSHRKMT2A | |
| SCHEMBL8478831 | 0.73 | TSHR (0.50) | ALDH1A1PBRM1KDM4EHSD17B10FABP3 | |
| SCHEMBL80183 | 0.73 | ALDH1A1 (0.64) | ALDH1A1PBRM1DPP4KDM4EHSD17B10 | |
| SCHEMBL6640962 | 0.73 | TSHR (0.53) | ALDH1A1PBRM1DPP4KDM4EHSD17B10 | |
| SCHEMBL9360259 | 0.72 | ALDH1A1 (0.48) | GAAALDH1A1KDM4EHSD17B10TSHR | |
| SCHEMBL1041643 | 0.71 | ALDH1A1 (0.61) | ALDH1A1PBRM1DPP4KDM4EHSD17B10 | |
| Hydrochloric Acid SCHEMBL8042412 | 0.71 | ALDH1A1 (0.61) | ALDH1A1PBRM1DPP4KDM4EHSD17B10 | |
| SCHEMBL7425018 | 0.71 | ALDH1A1 (0.61) | ALDH1A1PBRM1DPP4KDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5925647-A | TREATMENT OF INSULIN NON-INSULIN DEPENDENT DIABETES | SHAMAN PHARMACEUTICALS, INC. (US) | 1999-07-20 | — | — | US | disclosed |
| US-5681958-A | TREATMENT OF DIABETES | SHAMAN PHARMACEUTICALS, INC. (US) | 1997-10-28 | — | — | US | disclosed |
| WO-1996010015-A1 | CRYPTOLEPINE ANALOGS WITH HYPOGLYCEMIC ACTIVITY | SHAMAN PHARMACEUTICALS, INC. (US) | 1996-04-04 | — | — | WO | disclosed |