Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.37 |
| ▸ | CA2 | P00918 | 3/20 | 0.35 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA3 | P07451 | 2/20 | 0.35 |
| ▸ | CA4 | P22748 | 2/20 | 0.35 |
| ▸ | CA6 | P23280 | 2/20 | 0.35 |
| ▸ | CA5A | P35218 | 2/20 | 0.35 |
| ▸ | CA7 | P43166 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11397185 | 0.90 | CA1 (0.42) | L3MBTL1ALDH1A1HPGDHDAC8HDAC1 | |
| SCHEMBL11788977 | 0.85 | CISD1 (0.53) | CISD1L3MBTL1ALDH1A1POLBHPGD | |
| SCHEMBL11387454 | 0.81 | CISD1 (0.41) | CISD1L3MBTL1ALDH1A1POLBHPGD | |
| SCHEMBL11796619 | 0.80 | CISD1 (0.49) | CISD1L3MBTL1ALDH1A1POLBHPGD | |
| SCHEMBL11784489 | 0.76 | CA2 (0.47) | CISD1L3MBTL1ALDH1A1HPGDHSD17B10 | |
| SCHEMBL11802086 | 0.76 | CISD1 (0.45) | CISD1L3MBTL1ALDH1A1HPGDHSD17B10 | |
| SCHEMBL22922714 | 0.74 | CISD1 (0.50) | CISD1L3MBTL1ALDH1A1HPGDHSD17B10 | |
| SCHEMBL11788811 | 0.73 | ALDH1A1 (0.55) | CISD1ALDH1A1POLBHPGDHSD17B10 | |
| SCHEMBL11390793 | 0.73 | FBP1 (0.44) | L3MBTL1ALDH1A1POLBHPGDHSD17B10 | |
| SCHEMBL11849579 | 0.72 | CISD1 (0.48) | CISD1L3MBTL1ALDH1A1POLBHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0008367-B1 | N-ARYLSULFONYL PYRROLES, THEIR PREPARATION AND MEDICAMENTS CONTAINING THEM | BASF Aktiengesellschaft (DE) | 1983-08-10 | — | — | EP | disclosed |
| US-4288449-A | DIURETICS | BASF AKTIENGESELLSCHAFT (DE) | 1981-09-08 | — | — | US | disclosed |
| EP-0008367-A1 | N-Arylsulfonyl pyrroles, their preparation and medicaments containing them | BASF Aktiengesellschaft (DE) | 1980-03-05 | — | — | EP | disclosed |