SCHEMBL1115747

SCHEMBL1115747

Cn1c(=O)n(C)c2cc([N+](=O)[O-])c(N)cc21

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 7/20 0.59
▸ LMNA P02545 3/20 0.59
▸ HTT P42858 3/20 0.59
▸ ATAD2 Q6PL18 1/20 0.59
▸ KDM4E B2RXH2 1/20 0.59
▸ NPSR1 Q6W5P4 1/20 0.59
▸ S100B P04271 1/20 0.50
▸ KMT2A Q03164 2/20 0.49
▸ SMN1; SMN2 Q16637 3/20 0.48
▸ TSHR P16473 2/20 0.44
▸ CYP1A2 P05177 1/20 0.44
▸ CYP2C9 P11712 1/20 0.44
▸ CYP2C19 P33261 1/20 0.44
▸ TDP1 Q9NUW8 5/20 0.43
▸ MPI P34949 1/20 0.43
▸ ALDH1A1 P00352 5/20 0.43
▸ GAA P10253 1/20 0.43
▸ MEN1 O00255 1/20 0.43
▸ POLB P06746 1/20 0.43
▸ CYP3A4 P08684 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1115798 0.89 MAPT (0.76) MAPTLMNAHTTATAD2KDM4E
SCHEMBL12314599 0.88 MAPT (0.50) MAPTLMNAHTTATAD2KDM4E
SCHEMBL1115720 0.85 MAPT (0.47) MAPTLMNAHTTATAD2KDM4E
SCHEMBL30349789 0.84 MAPT (0.61) MAPTLMNAHTTATAD2KDM4E
SCHEMBL28991107 0.80 MAPT (0.61) MAPTLMNAHTTKDM4ENPSR1
SCHEMBL15005983 0.79 MAPT (0.59) MAPTLMNAHTTKDM4ENPSR1
SCHEMBL15324212 0.79 MAPT (0.59) MAPTLMNAHTTKDM4ENPSR1
SCHEMBL30896387 0.79 MAPT (0.59) MAPTLMNAHTTATAD2KDM4E
SCHEMBL1115528 0.77 ALDH1A1 (0.42) MAPTLMNAHTTKDM4ENPSR1
SCHEMBL8129306 0.77 MAPT (0.42) MAPTLMNAHTTATAD2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4741395-A1 NOVEL COMPOUND SENSITIVE TO NITROGEN MONOXIDE AND PHARMACEUTICAL COMPOSITION COMPRISING SAME Omniamed Co. Ltd (KR) 2026-05-13 — — EP disclosed
WO-2025009922-A1 NOVEL COMPOUND SENSITIVE TO NITROGEN MONOXIDE AND PHARMACEUTICAL COMPOSITION COMPRISING SAME 주식회사 옴니아메드 2025-01-09 — — WO disclosed
US-8262949-B2 Long wavelength shifted benzotriazole uv-absorbers and their use BASF SE (DE) 2012-09-11 — — US disclosed
US-8262949-B2 Long wavelength shifted benzotriazole uv-absorbers and their use BASF SE (DE) 2012-09-11 — — US disclosed
US-8262949-B2 Long wavelength shifted benzotriazole uv-absorbers and their use BASF SE (DE) 2012-09-11 — — US disclosed
EP-2032577-B1 LONG WAVELENGTH SHIFTED BENZOTRIAZOLE UV-ABSORBERS AND THEIR USE BASF SE (DE) 2011-02-02 — — EP disclosed
US-20100163813-A1 Long wavelength shifted benzotriazole uv-absorbers and their use CIBA CORPORATION 2010-07-01 — — US disclosed
US-20100163813-A1 Long wavelength shifted benzotriazole uv-absorbers and their use CIBA CORPORATION 2010-07-01 — — US disclosed
US-20100163813-A1 Long wavelength shifted benzotriazole uv-absorbers and their use CIBA CORPORATION 2010-07-01 — — US disclosed
EP-2032577-A1 LONG WAVELENGTH SHIFTED BENZOTRIAZOLE UV-ABSORBERS AND THEIR USE Ciba Holding Inc. (CH) 2009-03-11 — — EP disclosed
WO-2008000646-A1 LONG WAVELENGTH SHIFTED BENZOTRIAZOLE UV-ABSORBERS AND THEIR USE CIBA HOLDING INC. (CH) 2008-01-03 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100163813-A1 Long wavelength shifted benzotriazole uv-absorbers and their use SULT1A1, GABBR1, TPMT MAPT 136/4885LMNA 1593/4885HTT 292/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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