Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.53 |
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.48 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.47 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2740848 | 0.83 | HPGD (0.51) | RAB9AMAPTLMNASMN1; SMN2HPGD | |
| SCHEMBL8741848 | 0.79 | RAB9A (0.55) | NPC1RAB9AMAPTLMNASMN1; SMN2 | |
| SCHEMBL10493671 | 0.74 | NPC1 (0.51) | NPC1RAB9AMAPTSMN1; SMN2HPGD | |
| SCHEMBL5621851 | 0.74 | SMN1; SMN2 (0.58) | RAB9AMAPTLMNASMN1; SMN2HPGD | |
| SCHEMBL5621854 | 0.74 | SMN1; SMN2 (0.58) | RAB9AMAPTLMNASMN1; SMN2HPGD | |
| SCHEMBL9616080 | 0.72 | SIGMAR1 (0.59) | RAB9AMAPTLMNASMN1; SMN2HPGD | |
| SCHEMBL9616079 | 0.72 | SIGMAR1 (0.59) | RAB9AMAPTLMNASMN1; SMN2HPGD | |
| SCHEMBL10578992 | 0.71 | P2RX7 (0.52) | RAB9ASMN1; SMN2HPGDMEN1KMT2A | |
| SCHEMBL12443334 | 0.71 | MAPT (0.86) | MAPTLMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL4104467 | 0.71 | MAPT (0.76) | NPC1RAB9AMAPTLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4387150-A | HYDROPHOBIC GUANIDINE COMPOUND AS DEVELOPER | MITSUBISHI PAPER MILLS, LTD. (JP) | 1983-06-07 | — | — | US | disclosed |