SCHEMBL1115835

SCHEMBL1115835

COc1ccc(CCN(CCC(=O)NO)S(=O)(=O)c2ccc(NC(=O)NC(Cc3ccccc3)c3ccccc3)cc2)cc1

nearest known ligand 0.77

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
BMP1 P13497 20/20 0.77

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7002992 0.85 BMP1 (1.00) BMP1
SCHEMBL6999380 0.85 BMP1 (1.00) BMP1
SCHEMBL7004497 0.84 BMP1 (0.89) BMP1
SCHEMBL7001896 0.83 BMP1 (1.00) BMP1
SCHEMBL966010 0.82 BMP1 (1.00) BMP1
SCHEMBL966229 0.81 BMP1 (1.00) BMP1
SCHEMBL7008058 0.81 BMP1 (1.00) BMP1
SCHEMBL7000638 0.77 BMP1 (1.00) BMP1
SCHEMBL7003452 0.76 BMP1 (0.89) BMP1
SCHEMBL6997496 0.75 BMP1 (0.89) BMP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060216295-A1 Methods of identifying therapeutic targets for the treatment of vulvovaginal atrophy WYETH (US) 2006-09-28 US claimed
WO-2006099610-A2 METHODS OF IDENTIFYING THERAPEUTIC TARGETS FOR THE TREATMENT OF VULVOVAGINAL ATROPHY WYETH (US) 2006-09-21 WO claimed
US-20240182424-A1 ENHANCED ERYTHROPOIESIS AND IRON METABOLISM FIBROGEN, INC. (US) 2024-06-06 US disclosed
US-11680048-B2 Enhanced erythropoiesis and iron metabolism FIBROGEN, INC. (US) 2023-06-20 US disclosed
US-11680047-B2 Enhanced erythropoiesis and iron metabolism FIBROGEN, INC. (US) 2023-06-20 US disclosed
US-20210114987-A1 ENHANCED ERYTHROPOIESIS AND IRON METABOLISM FIBROGEN, INC. 2021-04-22 US disclosed
US-20210107878-A1 ENHANCED ERYTHROPOIESIS AND IRON METABOLISM FIBROGEN, INC. 2021-04-15 US disclosed
US-10927081-B2 Enhanced erythropoiesis and iron metabolism FIBROGEN, INC. (US) 2021-02-23 US disclosed
US-10894774-B2 Enhanced erythropoiesis and iron metabolism FIBROGEN, INC. (US) 2021-01-19 US disclosed
US-10882827-B2 Enhanced erythropoiesis and iron metabolism FIBROGEN, INC. (US) 2021-01-05 US disclosed
US-10626090-B2 Enhanced erythropoiesis and iron metabolism FIBROGEN INC. (US) 2020-04-21 US disclosed
US-20060258660-A1 Stabilization of hypoxia inducible factor (HIF) alpha FIBROGEN, INC. (US) 2006-11-16 US disclosed
US-20060216295-A1 Methods of identifying therapeutic targets for the treatment of vulvovaginal atrophy WYETH (US) 2006-09-28 US disclosed
WO-2006099610-A2 METHODS OF IDENTIFYING THERAPEUTIC TARGETS FOR THE TREATMENT OF VULVOVAGINAL ATROPHY WYETH (US) 2006-09-21 WO disclosed
US-20060183695-A1 Methods of increasing endogenous erythropoietin (EPO) FIBROGEN, INC. (US) 2006-08-17 US disclosed
US-20060178317-A1 Methods of increasing endogenous erythropoietin (EPO) FIBROGEN, INC. (US) 2006-08-10 US disclosed
US-20060178316-A1 Methods of increasing endogenous erythropoietin (EPO) FIBROGEN, INC. (US) 2006-08-10 US disclosed
US-20050020487-A1 Enhanced erythropoiesis and iron metabolism FIBROGEN, INC. 2005-01-27 US disclosed
US-20030176317-A1 Stabilization of hypoxia inducible factor (HIF) alpha FIBROGEN, INC. 2003-09-18 US disclosed
US-20030153503-A1 Methods of increasing endogenous erythropoietin (EPO) FIBROGEN, INC. 2003-08-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (17 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030176317-A1 Stabilization of hypoxia inducible factor (HIF) alpha HIF1A, HIF1AN, EGLN2 BMP1 2470/4885
US-20060178317-A1 Methods of increasing endogenous erythropoietin (EPO) EPOR, EGLN3, EGLN2 BMP1 659/4885
US-20060216295-A1 Methods of identifying therapeutic targets for the treatment of vulvovaginal atrophy DNASE1L3, ANXA4, SERPINA6 BMP1 4106/4885
US-11680048-B2 Enhanced erythropoiesis and iron metabolism EPOR, HAMP, TFRC BMP1 368/4885
US-11680047-B2 Enhanced erythropoiesis and iron metabolism EPOR, HAMP, TFRC BMP1 260/4885
US-20050020487-A1 Enhanced erythropoiesis and iron metabolism EPOR, HAMP, TFRC BMP1 368/4885
US-20240182424-A1 ENHANCED ERYTHROPOIESIS AND IRON METABOLISM EPOR, HAMP, TFRC BMP1 368/4885
US-20060183695-A1 Methods of increasing endogenous erythropoietin (EPO) EPOR, EGLN3, EGLN2 BMP1 659/4885
US-20030153503-A1 Methods of increasing endogenous erythropoietin (EPO) EPOR, EGLN3, EGLN2 BMP1 659/4885
US-10626090-B2 Enhanced erythropoiesis and iron metabolism EPOR, HAMP, TFRC BMP1 204/4885
US-20210114987-A1 ENHANCED ERYTHROPOIESIS AND IRON METABOLISM EPOR, HAMP, TFRC BMP1 368/4885
US-10894774-B2 Enhanced erythropoiesis and iron metabolism EPOR, HAMP, TFRC BMP1 368/4885
US-20060258660-A1 Stabilization of hypoxia inducible factor (HIF) alpha HIF1A, HIF1AN, EGLN2 BMP1 2470/4885
US-20210107878-A1 ENHANCED ERYTHROPOIESIS AND IRON METABOLISM EPOR, HAMP, TFRC BMP1 260/4885
US-10927081-B2 Enhanced erythropoiesis and iron metabolism EPOR, HAMP, TFRC BMP1 368/4885
US-10882827-B2 Enhanced erythropoiesis and iron metabolism EPOR, HAMP, TFRC BMP1 260/4885
US-20060178316-A1 Methods of increasing endogenous erythropoietin (EPO) EPOR, EGLN3, EGLN2 BMP1 659/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.