Sugi Predict

Sugi Predict / Compounds / SCHEMBL111587

SCHEMBL111587

SCHEMBL111587

Cc1ccnc(C(=O)O)c1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 5/20 0.61
▸ FTO Q9C0B1 5/20 0.61
▸ ALDH1A1 P00352 3/20 0.61
▸ ALKBH5 Q6P6C2 3/20 0.61
▸ KDM6B O15054 1/20 0.61
▸ TET3 O43151 1/20 0.61
▸ KDM4A O75164 1/20 0.61
▸ BBOX1 O75936 1/20 0.61
▸ MAPT P10636 1/20 0.61
▸ KDM5A P29375 1/20 0.61
▸ KDM5C P41229 1/20 0.61
▸ ASPH Q12797 1/20 0.61
▸ KDM4D Q6B0I6 1/20 0.61
▸ TET2 Q6N021 1/20 0.61
▸ KDM7A Q6ZMT4 1/20 0.61
▸ KDM8 Q8N371 1/20 0.61
▸ TET1 Q8NFU7 1/20 0.61
▸ EGLN2 Q96KS0 1/20 0.61
▸ EGLN1 Q9GZT9 1/20 0.61
▸ KDM4C Q9H3R0 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29758442 1.00 KDM4E (0.61) KDM4EFTOALDH1A1ALKBH5KDM6B
SCHEMBL2272913 0.98 KDM4E (0.59) KDM4EFTOALDH1A1ALKBH5KDM6B
SCHEMBL397492 0.83 ALDH1A1 (0.52) KDM4EFTOALDH1A1ALKBH5KDM6B
SCHEMBL29971476 0.83 ALDH1A1 (0.52) KDM4EFTOALDH1A1ALKBH5KDM6B
SCHEMBL3855479 0.82 UHRF1 (0.52) KDM4EFTOALDH1A1ALKBH5KDM6B
SCHEMBL3855482 0.82 UHRF1 (0.52) KDM4EFTOALDH1A1ALKBH5KDM6B
SCHEMBL23201148 0.81 KMO (0.65) KDM4EFTOALDH1A1ALKBH5KDM6B
SCHEMBL30882313 0.81 KMO (0.65) KDM4EFTOALDH1A1ALKBH5KDM6B
SCHEMBL5635022 0.81 UHRF1 (0.46) KDM4EFTOALDH1A1ALKBH5KDM6B
SCHEMBL23019932 0.81 UHRF1 (0.46) KDM4EFTOALDH1A1ALKBH5KDM6B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 437 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110167944-B Substituted pyrazoloazepin-4-ones and their use as phosphodiesterase inhibitors 联合疗法公司 2024-08-23 — — CN claimed
CN-111295382-B Bridged bicyclic compounds as farnesyl ester X receptor modulators 百时美施贵宝公司 2024-02-02 — — CN claimed
CN-115594843-B Synthesis method of electronic mediator, biosensor and preparation method of biosensor 可孚医疗科技股份有限公司 2023-12-12 — — CN claimed
CN-115594843-A Synthesis method of electron mediator, biosensor and preparation method of biosensor 可孚医疗科技股份有限公司（CN） 2023-01-13 — — CN claimed
US-20180355159-A1 ION EXCHANGE RESIN FOR PRODUCING BISPHENOL, AND A METHOD FOR PRODUCING BISPHENOL USING SAID ION EXCHANGE RESIN PTT GLOBAL CHEMICAL PUBLIC COMPANY LIMITED (TH) 2018-12-13 — — US claimed
EP-3386634-A2 ION EXCHANGE RESIN FOR PRODUCING BISPHENOL, AND A METHOD FOR PRODUCING BISPHENOL USING SAID ION EXCHANGE RESIN PTT Global Chemical Public Company Limited (TH) 2018-10-17 — — EP claimed
CN-108602057-A Ion exchange resin for producing bis-phenol PTT全球化学公共有限公司 2018-09-28 — — CN claimed
EP-3112352-A1 OPIOID RECEPTOR MODULATORS Janssen Pharmaceutica NV (BE) 2017-01-04 — — EP claimed
US-9428456-B2 1-[m-carboxamido(hetero)aryl-methyl]-heterocyclyl-carboxamide derivatives ACTELION PHARMACEUTICALS LTD (CH) 2016-08-30 — — US claimed
CN-103524401-B A kind of synthetic method of (2R, 4R)-4-methyl-2 piperidine carboxylic acid JIANGSU BAOZONG BAODA PHARMACEUTICAL CO.,LTD. (CN) 2016-01-20 — — CN claimed
EP-1982986-B1 PYRROLOPYRIDAZINONE COMPOUND AS PDE4 INHIBITOR UBE INDUSTRIES (JP) 2012-03-07 — — EP claimed
EP-1725537-B1 NOVEL COMPOUNDS AS OPIOID RECEPTOR MODULATORS JANSSEN PHARMACEUTICA NV (BE) 2011-07-13 — — EP claimed
CN-102105437-A Adamantyl diamide derivatives and uses of same LUNDBECK & CO AS H 2011-06-22 — — CN claimed
WO-2010128058-A1 DIHYDROPYRIMIDINONES FOR USE AS BACE2 INHIBITORS F. HOFFMANN-LA ROCHE AG (CH) 2010-11-11 — — WO claimed
US-20100286158-A1 DIHYDROPYRIMIDINONES HOFFMANN-LA ROCHE, INC. 2010-11-11 — — US claimed
US-20100022546-A1 ADAMANTYL DIAMIDE DERIVATIVES AND USES OF SAME H. LUNDBECK A/S (DK) 2010-01-28 — — US claimed
US-20090036453-A1 Pyrrolopyridazinone Compound UBE INDUSTRIES, LTD. (JP) 2009-02-05 — — US claimed
EP-1982986-A1 PYRROLOPYRIDAZINONE COMPOUND Ube Industries, Ltd. (JP) 2008-10-22 — — EP claimed
EP-0214158-A1 ANTHELMINTIC PYRIDINYL ACYLHYDRAZONES, METHOD OF USE AND COMPOSITIONS THE UPJOHN COMPANY (US) 1987-03-18 — — EP claimed
WO-1986004582-A1 ANTHELMINTIC PYRIDINYL ACYLHYDRAZONES, METHOD OF USE AND COMPOSITIONS THE UPJOHN COMPANY (US) 1986-08-14 — — WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180355159-A1 ION EXCHANGE RESIN FOR PRODUCING BISPHENOL, AND A METHOD FOR PRODUCING BISPHENOL USING SAID ION EXCHANGE RESIN JMJD6, HNRNPH3, TRRAP KDM4E 100/4885FTO 1126/4885ALDH1A1 2420/4885
US-20100022546-A1 ADAMANTYL DIAMIDE DERIVATIVES AND USES OF SAME QDPR, ADM2, PDE3B KDM4E 2749/4885FTO 1592/4885ALDH1A1 105/4885
US-20090036453-A1 Pyrrolopyridazinone Compound CBR3, CBR1, CYC1 KDM4E 1902/4885FTO 629/4885ALDH1A1 580/4885
US-20100286158-A1 DIHYDROPYRIMIDINONES BACE2, BACE1, PSEN2 KDM4E 2548/4885FTO 3801/4885ALDH1A1 563/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.