SCHEMBL397492

SCHEMBL397492

CC(=O)c1cc(C)ccn1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.52
UHRF1 Q96T88 1/20 0.48
CCR1 P32246 1/20 0.48
CCR5 P51681 1/20 0.48
CCR8 P51685 1/20 0.48
KDM4E B2RXH2 4/20 0.45
MEN1 O00255 3/20 0.45
KMT2A Q03164 3/20 0.45
NOS3 P29474 1/20 0.45
NOS1 P29475 1/20 0.45
NOS2 P35228 1/20 0.45
NPC1 O15118 6/20 0.41
RAB9A P51151 6/20 0.41
SMN1; SMN2 Q16637 5/20 0.41
PKM P14618 3/20 0.41
TP53 P04637 2/20 0.41
CTSA P10619 2/20 0.41
PLAU P00749 1/20 0.41
KDM6B O15054 1/20 0.41
TET3 O43151 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29971476 1.00 ALDH1A1 (0.52) ALDH1A1UHRF1CCR1CCR5CCR8
SCHEMBL29758442 0.83 KDM4E (0.61) ALDH1A1UHRF1CCR1CCR5CCR8
SCHEMBL111587 0.83 KDM4E (0.61) ALDH1A1UHRF1CCR1CCR5CCR8
SCHEMBL23019932 0.81 UHRF1 (0.46) ALDH1A1UHRF1CCR1CCR5CCR8
SCHEMBL2272913 0.81 KDM4E (0.59) ALDH1A1UHRF1CCR1CCR5CCR8
SCHEMBL29503141 0.81 CCR1 (0.52) UHRF1CCR1CCR5CCR8KDM4E
SCHEMBL5635022 0.81 UHRF1 (0.46) ALDH1A1UHRF1CCR1CCR5CCR8
SCHEMBL14037108 0.81 UHRF1 (0.46) ALDH1A1UHRF1CCR1CCR5CCR8
SCHEMBL106576 0.81 CCR1 (0.52) UHRF1CCR1CCR5CCR8KDM4E
SCHEMBL15201526 0.80 CCR1 (0.57) ALDH1A1UHRF1CCR1CCR5CCR8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 313 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116540465-B Electrochromic ion storage layer film and preparation method thereof NINGBO MI RUO ELECTRONIC TECHNOLOGY Co.,Ltd. (CN) 2026-05-26 CN claimed
CN-118130691-A Method for detecting characteristic components of typical aroma in main stream smoke of cigarettes 上海烟草集团有限责任公司 2024-06-04 CN claimed
WO-2024046712-A1 METHOD FOR PRODUCING A MATERIAL FOR A MEMBRANE, MATERIAL, MEMBRANE AND USE OF A MEMBRANE Forschungszentrum Jülich GmbH (DE) 2024-03-07 WO claimed
CN-116540465-A Novel electrochromic ion storage layer film and preparation method thereof 宁波祢若电子科技有限公司 2023-08-04 CN claimed
CN-113215861-A Baked sweet and fragrant cigarette paper and preparation method thereof 河南中烟工业有限责任公司 2021-08-06 CN claimed
CN-110423234-B Thiosemicarbazone derivative containing indole fragment and preparation method and application thereof 郑州大学 2020-06-30 CN claimed
CN-110423234-A Thiosemicarbazone derivative of the segment containing indoles and its preparation method and application UNIV ZHENGZHOU 2019-11-08 CN claimed
CN-106146390-A The synthetic method of medicine intermediate 2-acetyl-4-(2-methyl) pyridine 无锡乾浩生物医药有限公司 2016-11-23 CN claimed
CN-104313076-A Method for producing methylpyridinyl ethanol through biological catalysis UNIV QINGDAO SCIENCE & TECHNOLOGY 2015-01-28 CN claimed
US-20080254130-A1 Skin Antiaging & Brightening via Multi-function Treatment of Enzyme Dysfunction BIODERM RESEARCH (US) 2008-10-16 US claimed
US-20060074108-A1 Matrix metalloprotease (MMP) inhibitors and their application in cosmetic and pharmaceutical composition BIODERM RESEARCH (US) 2006-04-06 US claimed
CN-116540465-B Electrochromic ion storage layer film and preparation method thereof NINGBO MI RUO ELECTRONIC TECHNOLOGY Co.,Ltd. (CN) 2026-05-26 CN disclosed
EP-4705296-A1 HETEROARYLINDOLE INHIBITORS OF APOL-1 OmniAB, Inc. (US) 2026-03-11 EP disclosed
US-20260055113-A1 HETEROARYL COMPOUNDS FOR THE TREATMENT OF CANCER HOFFMANN-LA ROCHE INC. (US) 2026-02-26 US disclosed
US-12509446-B2 FYN and VEGFR2 kinase inhibitors ROTTAPHARM BIOTECH S.R.L. (IT) 2025-12-30 US disclosed
EP-1065206-A1 Tetrazolylalkyl indole compounds as anti-inflammatory and analgesic agents PFIZER INC. (US) 2001-01-03 EP disclosed
EP-1045833-A1 2,3-SUBSTITUTED INDOLE COMPOUNDS AS COX-2 INHIBITORS PFIZER INC. (US) 2000-10-25 EP disclosed
WO-2000049015-A1 PYRIDINE COMPOUNDS AND THEIR PHARMACEUTICAL USE FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2000-08-24 WO disclosed
EP-0974602-A1 Catalyst and process for hydrogenating olefinically unsaturated compound JSR Corporation (JP) 2000-01-26 EP disclosed
WO-1999035130-A1 2,3-SUBSTITUTED INDOLE COMPOUNDS AS COX-2 INHIBITORS PFIZER PHARMACEUTICALS INC. (JP) 1999-07-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260055113-A1 HETEROARYL COMPOUNDS FOR THE TREATMENT OF CANCER H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, HCCS, CLIC1 ALDH1A1 259/4885UHRF1 3902/4885CCR1 6/4885
US-12509446-B2 FYN and VEGFR2 kinase inhibitors FYN, LCK, LYN ALDH1A1 4279/4885UHRF1 1614/4885CCR1 949/4885
US-20080254130-A1 Skin Antiaging & Brightening via Multi-function Treatment of Enzyme Dysfunction PSMB1, PLOD3, CUTA ALDH1A1 330/4885UHRF1 244/4885CCR1 4807/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.