Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 8/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 8/20 | 0.40 |
| ▸ | PIK3CB | P42338 | 8/20 | 0.40 |
| ▸ | PIK3CG | P48736 | 8/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11000112 | 0.84 | CDK2 (0.40) | KMT2AALDH1A1MAPTMEN1NPC1 | |
| SCHEMBL12004940 | 0.82 | KMT2A (0.49) | KMT2AALDH1A1MAPTMEN1NPC1 | |
| SCHEMBL11320328 | 0.75 | JAK2 (0.40) | KMT2AALDH1A1MAPTMEN1NPC1 | |
| SCHEMBL11916724 | 0.74 | KMT2A (0.48) | KMT2AALDH1A1MAPTMEN1NPC1 | |
| SCHEMBL924920 | 0.73 | ALDH1A1 (0.51) | KMT2AALDH1A1MAPTMEN1NPC1 | |
| SCHEMBL10669262 | 0.73 | KMT2A (0.56) | KMT2AALDH1A1MAPTMEN1NPC1 | |
| SCHEMBL24426663 | 0.73 | NOTUM (0.39) | KMT2AALDH1A1MAPTMEN1NPC1 | |
| Hydrochloric Acid SCHEMBL10668153 | 0.71 | KMT2A (0.54) | KMT2AALDH1A1MAPTMEN1NPC1 | |
| SCHEMBL18616748 | 0.71 | PIK3CA (0.61) | KMT2AALDH1A1MAPTMEN1NPC1 | |
| SCHEMBL15651736 | 0.71 | BRD4 (0.45) | KMT2AALDH1A1MAPTMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4386097-A | Benzimidazoles, processes for their preparation and pharmaceutical preparations containing such compounds | CIBA-GEIGY CORPORATION (US) | 1983-05-31 | — | — | US | disclosed |