Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 7/20 | 0.38 |
| ▸ | PIK3CG | P48736 | 7/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 6/20 | 0.38 |
| ▸ | PIK3CB | P42338 | 6/20 | 0.38 |
| ▸ | CFTR | P13569 | 2/20 | 0.38 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11160835 | 0.73 | KMT2A (0.42) | PIK3CDPIK3CGPIK3CAPIK3CBALDH1A1 | |
| SCHEMBL12004940 | 0.70 | KMT2A (0.49) | PIK3CDPIK3CGPIK3CAPIK3CBALDH1A1 | |
| SCHEMBL20430936 | 0.69 | NOTUM (0.46) | NOTUMKIF11CFTRGPR55POLQ | |
| SCHEMBL11916724 | 0.69 | KMT2A (0.48) | PIK3CDPIK3CGPIK3CAPIK3CBALDH1A1 | |
| SCHEMBL924920 | 0.68 | ALDH1A1 (0.51) | PIK3CDPIK3CGPIK3CAPIK3CBALDH1A1 | |
| SCHEMBL10669262 | 0.68 | KMT2A (0.56) | PIK3CDPIK3CGPIK3CAPIK3CBALDH1A1 | |
| Hydrochloric Acid SCHEMBL10668153 | 0.66 | KMT2A (0.54) | PIK3CDPIK3CGPIK3CAPIK3CBALDH1A1 | |
| SCHEMBL16482021 | 0.66 | L3MBTL1 (0.54) | NOTUMKIF11GPR55NPC1LMNA | |
| SCHEMBL22628907 | 0.66 | NOTUM (0.49) | NOTUMKIF11GPR55ALDH1A1MAPT | |
| SCHEMBL15651736 | 0.66 | BRD4 (0.45) | PIK3CDPIK3CGPIK3CAPIK3CBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3998107-A1 | METHOD FOR PRODUCING INSULIN-PRODUCING CELL USING DIHYDROINDOLIZINONE DERIVATIVES | Tokyo Institute of Technology (JP) | 2022-05-18 | — | — | EP | disclosed |