Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1H | O95180 | 2/20 | 0.49 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7815135 | 0.88 | ADRA2C (0.59) | L3MBTL1TDP1ADRA2CALDH1A1ALOX12 | |
| SCHEMBL11158176 | 0.86 | NPSR1 (0.57) | L3MBTL1TDP1ADRA2CALDH1A1ALOX12 | |
| SCHEMBL11164283 | 0.86 | ADRA2C (0.47) | L3MBTL1ADRA2CALDH1A1ALOX12CYP3A4 | |
| SCHEMBL11163188 | 0.86 | L3MBTL1 (0.53) | L3MBTL1ADRA2CALDH1A1ALOX12CYP3A4 | |
| SCHEMBL9617102 | 0.82 | HPGD (0.50) | L3MBTL1TDP1ADRA2CALDH1A1ALOX12 | |
| SCHEMBL11165605 | 0.82 | ALDH1A1 (0.51) | CACNA1HCACNA1BL3MBTL1ADRA2CALDH1A1 | |
| SCHEMBL11166320 | 0.82 | ADRA2C (0.47) | CACNA1HCACNA1BL3MBTL1ADRA2CALDH1A1 | |
| SCHEMBL11166459 | 0.79 | ALDH1A1 (0.50) | L3MBTL1TDP1ADRA2CALDH1A1ALOX12 | |
| SCHEMBL11158092 | 0.78 | ALDH1A1 (0.52) | L3MBTL1TDP1ADRA2CALDH1A1ALOX12 | |
| SCHEMBL11165536 | 0.78 | EPHX1 (0.60) | L3MBTL1TDP1ALDH1A1ALOX12CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4423167-A | POLYMERIC POLYOL, POLYESTER CROSSLINKER AND CATALYST | PPG INDUSTRIES, INC. (US) | 1983-12-27 | — | — | US | disclosed |
| EP-0017484-B1 | 2-IMIDAZOLINE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND THE PHARMACEUTICAL COMPOSITION OF THE SAME | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1983-04-06 | — | — | EP | disclosed |
| EP-0017484-A1 | 2-Imidazoline derivatives, process for the preparation thereof and the pharmaceutical composition of the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1980-10-15 | — | — | EP | disclosed |