Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM2 | P50570 | 7/20 | 0.64 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | KCNH3 | Q9ULD8 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13330002 | 1.00 | DNM2 (0.64) | DNM2GPR84MAPK1ALDH1A1LMNA | |
| SCHEMBL13329946 | 0.82 | DNM2 (0.81) | DNM2MAPK1ALDH1A1LMNATSHR | |
| SCHEMBL13329945 | 0.82 | DNM2 (0.81) | DNM2MAPK1ALDH1A1LMNATSHR | |
| SCHEMBL9589312 | 0.81 | DNM2 (0.63) | DNM2MAPK1ALDH1A1LMNATSHR | |
| SCHEMBL13330001 | 0.81 | DNM2 (0.64) | DNM2MAPK1ALDH1A1LMNATSHR | |
| SCHEMBL1194281 | 0.80 | DNM2 (0.78) | DNM2MAPK1ALDH1A1LMNATSHR | |
| SCHEMBL13329951 | 0.79 | DNM2 (0.77) | DNM2MAPK1ALDH1A1LMNATSHR | |
| SCHEMBL7865350 | 0.79 | KMT2A (0.50) | MAPK1ALDH1A1LMNATSHRTP53 | |
| SCHEMBL14441528 | 0.76 | KMT2A (0.67) | DNM2HTTKMT2AKCNH3MAPT | |
| SCHEMBL14441519 | 0.76 | KMT2A (0.67) | DNM2HTTKMT2AKCNH3MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4402730-A | Pyrimidine derivatives and their use as herbicides | SANDOZ LTD. (CH) | 1983-09-06 | — | — | US | disclosed |