Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM2 | P50570 | 9/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | KCNH3 | Q9ULD8 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.43 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9376298 | 0.93 | DNM2 (0.55) | DNM2KMT2AMAPK1ALDH1A1LMNA | |
| SCHEMBL2574542 | 0.88 | KMT2A (0.56) | DNM2KMT2AMAPK1ALDH1A1LMNA | |
| SCHEMBL12963418 | 0.86 | KMT2A (0.50) | DNM2KMT2AMAPK1ALDH1A1LMNA | |
| SCHEMBL10811629 | 0.83 | KMT2A (0.49) | DNM2KMT2AMAPK1ALDH1A1LMNA | |
| SCHEMBL13329946 | 0.82 | DNM2 (0.81) | DNM2KMT2AMAPK1ALDH1A1LMNA | |
| SCHEMBL13329945 | 0.82 | DNM2 (0.81) | DNM2KMT2AMAPK1ALDH1A1LMNA | |
| SCHEMBL9589312 | 0.81 | DNM2 (0.63) | DNM2KMT2AMAPK1ALDH1A1LMNA | |
| SCHEMBL11162964 | 0.81 | DNM2 (0.64) | DNM2KMT2AMAPK1ALDH1A1LMNA | |
| SCHEMBL13330002 | 0.81 | DNM2 (0.64) | DNM2KMT2AMAPK1ALDH1A1LMNA | |
| SCHEMBL1194281 | 0.80 | DNM2 (0.78) | DNM2KMT2AMAPK1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7722893-B2 | Use of substitute 2,4-bis (alkylamino) pyrimidines or quinzolines as antimicrobials | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2010-05-25 | — | — | US | disclosed |
| US-7722893-B2 | Use of substitute 2,4-bis (alkylamino) pyrimidines or quinzolines as antimicrobials | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2010-05-25 | — | — | US | disclosed |