Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM2 | P50570 | 10/20 | 0.78 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.67 |
| ▸ | TP53 | P04637 | 1/20 | 0.67 |
| ▸ | TSHR | P16473 | 1/20 | 0.67 |
| ▸ | HTT | P42858 | 1/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.67 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.61 |
| ▸ | ESR1 | P03372 | 1/20 | 0.55 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.55 |
| ▸ | KCNH3 | Q9ULD8 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13329945 | 0.98 | DNM2 (0.81) | DNM2ALDH1A1MAPK1LMNATP53 | |
| SCHEMBL13329946 | 0.98 | DNM2 (0.81) | DNM2ALDH1A1MAPK1LMNATP53 | |
| SCHEMBL13329951 | 0.95 | DNM2 (0.77) | DNM2ALDH1A1MAPK1LMNATP53 | |
| SCHEMBL16608857 | 0.95 | ALDH1A1 (0.73) | DNM2ALDH1A1MAPK1LMNATP53 | |
| SCHEMBL25474229 | 0.89 | DNM2 (1.00) | DNM2ALDH1A1MAPK1LMNATP53 | |
| SCHEMBL16608745 | 0.87 | DNM2 (0.61) | DNM2ALDH1A1MAPK1LMNATP53 | |
| SCHEMBL9589312 | 0.83 | DNM2 (0.63) | DNM2ALDH1A1MAPK1LMNATP53 | |
| SCHEMBL13329947 | 0.83 | LMNA (0.83) | DNM2ALDH1A1MAPK1LMNATP53 | |
| SCHEMBL13309799 | 0.83 | TLR8 (0.61) | DNM2ALDH1A1MAPK1LMNATP53 | |
| SCHEMBL13309816 | 0.83 | TLR8 (0.61) | DNM2ALDH1A1MAPK1LMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7887845-B2 | Particle of a solid dispersion composed of a water soluble polymer and etravirine or salt thereof; etravirine FDA Orange book listed patent | JANSSEN PHARMACEUTICA NV (BE) | 2011-02-15 | — | — | US | disclosed |
| US-20100172970-A1 | ANTIVIRAL COMPOSITIONS | VERRECK GEERT | 2010-07-08 | — | — | US | disclosed |
| EP-1648524-B1 | USE OF SUBSTITUTED 2,4-BIS (ALKYLAMINO) PYRIMIDINES OR -QUINAZOLINES AS ANTIMICROBIALS | CIBA HOLDING INC (CH) | 2009-01-14 | — | — | EP | disclosed |
| US-20070196478-A1 | ANTIVIRAL COMPOSITIONS | VERRECK GEERT | 2007-08-23 | — | — | US | disclosed |
| US-7241458-B1 | Antiviral compositions | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-07-10 | — | — | US | disclosed |
| US-20060127487-A1 | Antiviral compositions | VERRECK GEERT | 2006-06-15 | — | — | US | disclosed |
| EP-1225874-B1 | ANTIVIRAL SOLID DISPERSIONS | JANSSEN PHARMACEUTICA NV (BE) | 2006-02-01 | — | — | EP | disclosed |
| EP-1225874-A1 | ANTIVIRAL COMPOSITIONS | Janssen Pharmaceutica N.V. (BE) | 2002-07-31 | — | — | EP | disclosed |
| WO-2001022938-A1 | ANTIVIRAL COMPOSITIONS | JANSSEN PHARMACEUTICA N.V. (BE) | 2001-04-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070196478-A1 | ANTIVIRAL COMPOSITIONS | EIF2AK2, ZC3HAV1, RPL35 | DNM2 800/4885ALDH1A1 3865/4885MAPK1 3898/4885 |
| US-20100172970-A1 | ANTIVIRAL COMPOSITIONS | EIF2AK2, ZC3HAV1, RPL35 | DNM2 800/4885ALDH1A1 3865/4885MAPK1 3898/4885 |
| US-20060127487-A1 | Antiviral compositions | EIF2AK2, ZC3HAV1, RPL35 | DNM2 800/4885ALDH1A1 3865/4885MAPK1 3898/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.