Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 5/20 | 0.44 |
| ▸ | CA9 | Q16790 | 5/20 | 0.44 |
| ▸ | CA1 | P00915 | 4/20 | 0.44 |
| ▸ | CA12 | O43570 | 4/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | CA6 | P23280 | 1/20 | 0.44 |
| ▸ | CA5A | P35218 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | AGO2 | Q9UKV8 | 1/20 | 0.44 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.44 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MPO | P05164 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2051521 | 0.84 | GRIA4 (0.43) | CA2CA9CA1CA12TSHR | |
| SCHEMBL1044702 | 0.82 | CA1 (0.48) | CA2CA9CA1CA12CA6 | |
| SCHEMBL4769301 | 0.80 | APLNR (0.41) | CA2CA9CA1CA12ALDH1A1 | |
| Sulfamide SCHEMBL11473091 | 0.79 | CA2 (0.46) | CA2CA9CA1CA12TSHR | |
| SCHEMBL18028786 | 0.79 | PTGES2 (0.44) | CA2CA9CA1CA12CA14 | |
| Sulfamide SCHEMBL11474863 | 0.79 | CA2 (0.46) | CA2CA9CA1CA12TSHR | |
| SCHEMBL1792962 | 0.79 | PTGES2 (0.44) | CA2CA9CA1CA12CA14 | |
| SCHEMBL18028833 | 0.79 | PTGES2 (0.44) | CA2CA9CA1CA12CA14 | |
| SCHEMBL11562753 | 0.78 | ALDH1A1 (0.45) | CA2CA9CA1CA12TSHR | |
| Hydrochloric Acid SCHEMBL7559873 | 0.77 | ALDH1A1 (0.43) | CA2CA9CA1CA12CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2556068-A1 | P38 MAP KINASE INHIBITORS | Respivert Limited (GB) | 2013-02-13 | — | — | EP | disclosed |
| US-4413011-A | Substituted 2,2-dimethyl-5-phenoxypentanoic acid benzamides as anti-arteriosclerotic agents and method | WARNER-LAMBERT COMPANY (US) | 1983-11-01 | — | — | US | disclosed |