Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT5 | Q9NXA8 | 4/20 | 0.77 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.77 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.77 |
| ▸ | NME4 | O00746 | 2/20 | 0.77 |
| ▸ | GCDH | Q92947 | 2/20 | 0.77 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.77 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.77 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.77 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.77 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.77 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.77 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.77 |
| ▸ | HTR3A | P46098 | 1/20 | 0.77 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.77 |
| ▸ | MEN1 | O00255 | 3/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
| ▸ | BLVRB | P30043 | 2/20 | 0.62 |
| ▸ | PDE4A | P27815 | 1/20 | 0.62 |
| ▸ | KDR | P35968 | 1/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ipsalazide SCHEMBL596652 | 1.00 | SIRT5 (0.77) | SIRT5TDP1HRH3NME4GCDH | |
| Balsalazide SCHEMBL3267109 | 0.87 | SIRT5 (1.00) | SIRT5TDP1HRH3NME4GCDH | |
| Balsalazide SCHEMBL29377041 | 0.87 | SIRT5 (1.00) | SIRT5TDP1HRH3NME4GCDH | |
| Balsalazide SCHEMBL138311 | 0.87 | SIRT5 (1.00) | SIRT5TDP1HRH3NME4GCDH | |
| Balsalazide SCHEMBL118300 | 0.87 | SIRT5 (1.00) | SIRT5TDP1HRH3NME4GCDH | |
| Balsalazide SCHEMBL134019 | 0.86 | SIRT5 (0.97) | SIRT5TDP1HRH3NME4GCDH | |
| Balsalazide SCHEMBL7908058 | 0.86 | SIRT5 (0.97) | SIRT5TDP1HRH3NME4GCDH | |
| Balsalazide SCHEMBL28818120 | 0.86 | SIRT5 (0.97) | SIRT5TDP1HRH3NME4GCDH | |
| Balsalazide SCHEMBL5598491 | 0.86 | SIRT5 (0.97) | SIRT5TDP1HRH3NME4GCDH | |
| SCHEMBL11160268 | 0.85 | SIRT5 (0.79) | SIRT5TDP1HRH3NME4GCDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4412992-A | 2-Hydroxy-5-phenylazobenzoic acid derivatives and method of treating ulcerative colitis therewith | BIOREX LABORATORIES LIMITED (GB) | 1983-11-01 | — | — | US | claimed |
| CN-111529684-A | Use of oral sustained release compositions containing cyclosporin | 卓越治疗有限公司 | 2020-08-14 | — | — | CN | disclosed |
| US-4412992-A | 2-Hydroxy-5-phenylazobenzoic acid derivatives and method of treating ulcerative colitis therewith | BIOREX LABORATORIES LIMITED (GB) | 1983-11-01 | — | — | US | disclosed |