Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 2/20 | 0.53 |
| ▸ | CTSK | P43235 | 2/20 | 0.53 |
| ▸ | BACE1 | P56817 | 6/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.41 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.41 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.41 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.41 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.41 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | REN | P00797 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12835706 | 0.90 | CTSS (0.56) | CTSSCTSKBACE1CA2CA1 | |
| SCHEMBL29558421 | 0.90 | CTSS (0.56) | CTSSCTSKBACE1CA2CA1 | |
| SCHEMBL11163088 | 0.89 | CTSK (0.49) | CTSSCTSKBACE1CA2PSENEN | |
| SCHEMBL10308404 | 0.88 | CTSS (0.54) | CTSSCTSKBACE1CA2PSENEN | |
| SCHEMBL17446797 | 0.87 | CTSS (0.53) | CTSSCTSKBACE1CA2PSENEN | |
| SCHEMBL9224622 | 0.87 | KMT2A (0.43) | CTSSCTSKCA2CA1CA7 | |
| SCHEMBL18953129 | 0.87 | KMT2A (0.43) | CTSSCTSKCA2CA1CA7 | |
| SCHEMBL18953127 | 0.87 | KMT2A (0.43) | CTSSCTSKCA2CA1CA7 | |
| SCHEMBL10606976 | 0.86 | CTSK (0.47) | CTSSCTSKCA2CA1CA7 | |
| SCHEMBL7509222 | 0.86 | CTSK (0.47) | CTSSCTSKCA2CA1CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4369178-A | Glucosamine peptide derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1983-01-18 | — | — | US | disclosed |
| EP-0014984-B1 | GLUCOSAMINE-PEPTIDE DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1982-12-01 | — | — | EP | disclosed |
| EP-0014984-A1 | Glucosamine-peptide derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1980-09-03 | — | — | EP | disclosed |