SCHEMBL18953129

SCHEMBL18953129

CC(NC(=O)OC(C)(C)C)C(=O)NC(CCC(=O)O)C(N)=O

nearest known ligand 0.51

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 1/20 0.43
▸ NOD2 Q9HC29 1/20 0.42
▸ REN P00797 4/20 0.41
▸ CTSK P43235 7/20 0.41
▸ CTSS P25774 6/20 0.41
▸ CTSL P07711 1/20 0.41
▸ CTSB P07858 1/20 0.41
▸ CA1 P00915 1/20 0.39
▸ CA2 P00918 1/20 0.39
▸ CA7 P43166 1/20 0.39
▸ ERAP2 Q6P179 1/20 0.39
▸ ERAP1 Q9NZ08 1/20 0.39
▸ LNPEP Q9UIQ6 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18953127 1.00 KMT2A (0.43) KMT2ANOD2RENCTSKCTSS
SCHEMBL9224622 1.00 KMT2A (0.43) KMT2ANOD2RENCTSKCTSS
SCHEMBL9696051 0.89 FOLH1 (0.48) KMT2ACTSKCTSSCTSLCTSB
SCHEMBL10976677 0.89 FOLH1 (0.48) KMT2ACTSKCTSSCTSLCTSB
SCHEMBL10606976 0.89 CTSK (0.47) RENCTSKCTSSCTSLCTSB
SCHEMBL8461423 0.89 CTSK (0.47) RENCTSKCTSSCTSLCTSB
SCHEMBL7509222 0.89 CTSK (0.47) RENCTSKCTSSCTSLCTSB
SCHEMBL11120073 0.87 NOD1 (0.46) KMT2ARENCTSKCTSSCTSL
SCHEMBL11165901 0.87 CTSS (0.53) RENCTSKCTSSCA1CA2
SCHEMBL10788830 0.84 REN (0.47) KMT2ARENCTSKCTSSCTSL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3389643-B1 NOVEL MURAMYL PEPTIDE DERIVATIVE COMPOUND, SYNTHESIS AND USES THEREOF BHARAT BIOTECH INT LTD (IN) 2023-05-03 — — EP disclosed
CN-108884132-B Muramyl peptide derivatives a compound their synthesis and their use 巴拉特生物技术国际有限公司 2022-10-04 — — CN disclosed
EP-3387005-B1 NOVEL MURAMYL PEPTIDE DERIVATIVE COMPOUND, SYNTHESIS AND USES THEREOF BHARAT BIOTECH INT LTD (IN) 2022-08-24 — — EP disclosed
US-20220056080-A1 Muramyl Peptide Derivatives BHARAT BIOTECH INTERNATIONAL LIMITED (IN) 2022-02-24 — — US disclosed
US-10927147-B2 Muramyl peptide derivative compound, synthesis and uses thereof BHARAT BIOTECH INTERNATIONAL LIMITED (IN) 2021-02-23 — — US disclosed
US-10576147-B2 Muramyl peptide derivative compound, synthesis and uses thereof BHARAT BIOTECH INTERNATIONAL LIMITED (IN) 2020-03-03 — — US disclosed
US-20180371023-A1 NOVEL MURAMYL PEPTIDE DERIVATIVE COMPOUND, SYNTHESIS AND USES THEREOF BHARAT BIOTECH INTERNATIONAL LIMITED (IN) 2018-12-27 — — US disclosed
US-20180360957-A1 NOVEL MURAMYL PEPTIDE DERIVATIVE COMPOUND, SYNTHESIS AND USES THEREOF BHARAT BIOTECH INTERNATIONAL LIMITED (IN) 2018-12-20 — — US disclosed
EP-3389643-A1 NOVEL MURAMYL PEPTIDE DERIVATIVE COMPOUND, SYNTHESIS AND USES THEREOF Bharat Biotech International Limited (IN) 2018-10-24 — — EP disclosed
EP-3387005-A1 NOVEL MURAMYL PEPTIDE DERIVATIVE COMPOUND, SYNTHESIS AND USES THEREOF Bharat Biotech International Limited (IN) 2018-10-17 — — EP disclosed
WO-2017103944-A1 NOVEL MURAMYL PEPTIDE DERIVATIVE COMPOUND, SYNTHESIS AND USES THEREOF BHARAT BIOTECH INTERNATIONAL LIMITED (IN) 2017-06-22 — — WO disclosed
WO-2017098529-A1 NOVEL MURAMYL PEPTIDE DERIVATIVE COMPOUND, SYNTHESIS AND USES THEREOF BHARAT BIOTECH INTERNATIONAL LIMITED (IN) 2017-06-15 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220056080-A1 Muramyl Peptide Derivatives NOD2, NGLY1, LNPEP KMT2A 3063/4885NOD2 1/4885REN 3471/4885
US-20180360957-A1 NOVEL MURAMYL PEPTIDE DERIVATIVE COMPOUND, SYNTHESIS AND USES THEREOF NOD2, HM13, HLA-DRB1 KMT2A 2963/4885NOD2 1/4885REN 3492/4885
US-10576147-B2 Muramyl peptide derivative compound, synthesis and uses thereof NOD2, HM13, QRFPR KMT2A 2936/4885NOD2 1/4885REN 3267/4885
US-20180371023-A1 NOVEL MURAMYL PEPTIDE DERIVATIVE COMPOUND, SYNTHESIS AND USES THEREOF NOD2, MICA, TLR9 KMT2A 2775/4885NOD2 1/4885REN 3414/4885
US-10927147-B2 Muramyl peptide derivative compound, synthesis and uses thereof NOD2, TLR9, MICA KMT2A 2643/4885NOD2 1/4885REN 3261/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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