Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.42 |
| ▸ | REN | P00797 | 4/20 | 0.41 |
| ▸ | CTSK | P43235 | 7/20 | 0.41 |
| ▸ | CTSS | P25774 | 6/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.39 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.39 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18953127 | 1.00 | KMT2A (0.43) | KMT2ANOD2RENCTSKCTSS | |
| SCHEMBL18953129 | 1.00 | KMT2A (0.43) | KMT2ANOD2RENCTSKCTSS | |
| SCHEMBL9696051 | 0.89 | FOLH1 (0.48) | KMT2ACTSKCTSSCTSLCTSB | |
| SCHEMBL10976677 | 0.89 | FOLH1 (0.48) | KMT2ACTSKCTSSCTSLCTSB | |
| SCHEMBL10606976 | 0.89 | CTSK (0.47) | RENCTSKCTSSCTSLCTSB | |
| SCHEMBL8461423 | 0.89 | CTSK (0.47) | RENCTSKCTSSCTSLCTSB | |
| SCHEMBL7509222 | 0.89 | CTSK (0.47) | RENCTSKCTSSCTSLCTSB | |
| SCHEMBL11120073 | 0.87 | NOD1 (0.46) | KMT2ARENCTSKCTSSCTSL | |
| SCHEMBL11165901 | 0.87 | CTSS (0.53) | RENCTSKCTSSCA1CA2 | |
| SCHEMBL10788830 | 0.84 | REN (0.47) | KMT2ARENCTSKCTSSCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5416070-A | Composition for macrophage activation | IMMUNOTHERAPEUTICS, INC. (US) | 1995-05-16 | — | — | US | disclosed |
| EP-0527803-A1 | COMPOSITION FOR MACROPHAGE ACTIVATION. | IMMUNOTHERAPEUTICS INC (US) | 1993-02-24 | — | — | EP | disclosed |
| EP-0426667-A4 | COMPOSITION FOR MACROPHAGE ACTIVATION | — | 1992-05-06 | — | — | EP | disclosed |
| WO-1991016347-A1 | COMPOSITION FOR MACROPHAGE ACTIVATION | IMMUNOTHERAPEUTICS, INC. (US) | 1991-10-31 | — | — | WO | disclosed |
| EP-0426667-A1 | COMPOSITION FOR MACROPHAGE ACTIVATION. | IMMUNOTHERAPEUTICS INC (US) | 1991-05-15 | — | — | EP | disclosed |
| US-4950645-A | ANTITUMOR AGENTS; NONTOXIC; ACTIVATES HUMAN MONOCYTES | IMMUNOTHERAPEUTICS, INC. (US) | 1990-08-21 | — | — | US | disclosed |
| WO-1990000396-A1 | COMPOSITION FOR MACROPHAGE ACTIVATION | IMMUNOTHERAPEUTICS, INC. (US) | 1990-01-25 | — | — | WO | disclosed |
| EP-0098520-B1 | L-ALANYL-D-ISOGLUTAMINYL-ADAMANTYL AMIDE, PROCESS FOR ITS PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THIS COMPOUND | SPOFA Spojené Podniky Pro Zdravotnickou Vyrobu (CS) | 1986-01-29 | — | — | EP | disclosed |
| US-4515715-A | IMMUNOSTIMULANTS, IMMUNOADJUVANTS | SPOFA, SPOJENE PODNIKY PRO ZDRATVONICKOU VYROBU (CS) | 1985-05-07 | — | — | US | disclosed |
| EP-0098520-A1 | L-alanyl-D-isoglutaminyl-adamantyl amide, process for its preparation and pharmaceutical compositions containing this compound | SPOFA Spojené Podniky Pro Zdravotnickou Vyrobu (CS) | 1984-01-18 | — | — | EP | disclosed |
| EP-0004512-B1 | MURAMYL-PEPTIDE ESTER DERIVATIVES AND THEIR APPLICATION TO PHARMACOLOGICAL COMPOSITIONS AND LABORATORY REACTANTS | ANVAR Agence Nationale de Valorisation de la Recherche (FR) | 1984-01-18 | — | — | EP | disclosed |
| US-4396607-A | IMMUNOLOGY, ANTIGENS | AGENCE NATIONALE DE VALORISATION DE LA RECHERCHE (ANVAR) (FR) | 1983-08-02 | — | — | US | disclosed |
| EP-0013856-B1 | NEW COMPOUNDS ASSOCIATING PEPTIDYL OR AMINOACYL RESIDUES TO LIPOPHILIC GROUPS AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAID NEW COMPOUNDS | ANVAR Agence Nationale de Valorisation de la Recherche (FR) | 1983-03-09 | — | — | EP | disclosed |
| US-4370265-A | N-ACETYLMURAMYL-L-ALANYL-D-GLUTAMIC ACID | AGENCE NATIONALE DE VALORISATION (FR) | 1983-01-25 | — | — | US | disclosed |
| US-4335111-A | BACTERICIDES | AGENCE NATIONAL DE VALORISATION DE LA RECHERCHE (ANVAR) (FR) | 1982-06-15 | — | — | US | disclosed |
| US-4235771-A | ACYL-MURAMIC ACID WITH PEPTIDE CHAIN LINKED THERETO | AGENCE NATIONALE DE VALORISATION DE LA RECHERCHE (ANVAR) (FR) | 1980-11-25 | — | — | US | disclosed |
| EP-0013856-A1 | New compounds associating peptidyl or aminoacyl residues to lipophilic groups and pharmaceutical compositions containing said new compounds | ANVAR Agence Nationale de Valorisation de la Recherche (FR) | 1980-08-06 | — | — | EP | disclosed |
| US-4186194-A | Water soluble agents effective as immunological adjuvants for stimulating, in the host the immune response to various antigens and compositions, notably vaccines containing said water soluble agents | AGENCE NATIONALE DE VALORISATION DE LA RECHERCHE (ANVAR) (FR) | 1980-01-29 | — | — | US | disclosed |
| WO-1979000802-A1 | NEW ESTER COMPOUNDS OF MURAMYL-PEPTIDE AND APPLICATIONS THEREOF TO PHARMACEUTICAL COMPOSITIONS AND LABORATORY REACTA | ANVAR (FR) | 1979-10-18 | — | — | WO | disclosed |
| EP-0004512-A1 | Muramyl-peptide ester derivatives and their application to pharmacological compositions and laboratory reactants | ANVAR Agence Nationale de Valorisation de la Recherche (FR) | 1979-10-03 | — | — | EP | disclosed |