Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 10/20 | 0.47 |
| ▸ | CTSS | P25774 | 10/20 | 0.47 |
| ▸ | CTSL | P07711 | 3/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | REN | P00797 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | PTPRB | P23467 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10376680 | 0.85 | CTSK (0.47) | CTSKCTSSCTSLCTSBREN | |
| SCHEMBL10376679 | 0.85 | CTSK (0.47) | CTSKCTSSCTSLCTSBREN | |
| SCHEMBL6649258 | 0.83 | CTSK (0.48) | CTSKCTSSCTSLCTSBREN | |
| SCHEMBL6753883 | 0.83 | CTSK (0.46) | CTSKCTSSCTSLCTSBREN | |
| SCHEMBL11412683 | 0.82 | CTSK (0.45) | CTSKCTSSCTSLCTSBREN | |
| SCHEMBL6647750 | 0.82 | CTSK (0.47) | CTSKCTSSCTSLCTSBREN | |
| SCHEMBL18511282 | 0.82 | REN (0.46) | CTSKCTSSCTSLRENMAPT | |
| SCHEMBL21714671 | 0.81 | CTSK (0.47) | CTSKCTSSCTSLRENMAPT | |
| SCHEMBL11169198 | 0.80 | CTSS (0.47) | CTSKCTSSCTSLCTSBREN | |
| SCHEMBL10376375 | 0.80 | CTSK (0.46) | CTSKCTSSCTSLMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4385176-A | RING EXPANSION USING A LEWIS ACID | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1983-05-24 | — | — | US | disclosed |
| US-4308380-A | 2-Lower alkyl-2 or 3-cephem-4-carboxylic acid derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1981-12-29 | — | — | US | disclosed |
| US-4113940-A | ANTIMICROBIAL | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1978-09-12 | — | — | US | disclosed |