Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 10/20 | 0.47 |
| ▸ | CTSS | P25774 | 4/20 | 0.44 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | PTPRB | P23467 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | REN | P00797 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6753883 | 0.92 | CTSK (0.46) | CTSKCTSSCTSLMAPTPPARA | |
| SCHEMBL10376679 | 0.87 | CTSK (0.47) | CTSKCTSSCTSLPPARAPTPRB | |
| SCHEMBL10376680 | 0.87 | CTSK (0.47) | CTSKCTSSCTSLPPARAPTPRB | |
| SCHEMBL6649258 | 0.82 | CTSK (0.48) | CTSKCTSSCTSLPPARAATM | |
| SCHEMBL5168568 | 0.81 | CTSK (0.43) | CTSKCTSSCTSLMAPTPTPRB | |
| SCHEMBL18511282 | 0.81 | REN (0.46) | CTSKCTSSCTSLMAPTPTPRB | |
| SCHEMBL11412683 | 0.81 | CTSK (0.45) | CTSKCTSSCTSLMAPTPPARA | |
| SCHEMBL11166172 | 0.81 | CTSK (0.47) | CTSKCTSSCTSLMAPTPTPRB | |
| SCHEMBL6647750 | 0.81 | CTSK (0.47) | CTSKCTSSCTSLMAPTPTPRB | |
| SCHEMBL14559227 | 0.79 | CTSK (0.40) | CTSKCTSSCTSLMAPTPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10836761-B2 | Cinchonine-derived catalysts and methods of using same | BRANDEIS UNIVERSITY (US) | 2020-11-17 | — | — | US | disclosed |
| US-20200048243-A1 | CINCHONINE-DERIVED CATALYSTS AND METHODS OF USING SAME | BRANDEIS UNIVERSITY (US) | 2020-02-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10836761-B2 | Cinchonine-derived catalysts and methods of using same | MCM2, MCM7, MCM5 | CTSK 1231/4885CTSS 775/4885CTSL 2479/4885 |
| US-20200048243-A1 | CINCHONINE-DERIVED CATALYSTS AND METHODS OF USING SAME | MCM2, MCM7, MCM5 | CTSK 1231/4885CTSS 775/4885CTSL 2479/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.