Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 2/20 | 0.56 |
| ▸ | QPCT | Q16769 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 5/20 | 0.49 |
| ▸ | DRD3 | P35462 | 2/20 | 0.49 |
| ▸ | DRD2 | P14416 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | HRH1 | P35367 | 1/20 | 0.49 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.49 |
| ▸ | KIT | P10721 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.48 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.48 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11166237 | 0.84 | HTR1A (0.50) | QPCTHTR1ADRD3DRD2HTR2A | |
| SCHEMBL11161966 | 0.84 | HTR1A (0.52) | HTR7QPCTHTR1ADRD3DRD2 | |
| SCHEMBL11165829 | 0.84 | DRD2 (0.62) | HTR7QPCTHTR1ADRD2HTR2A | |
| Hydrochloric Acid SCHEMBL11167530 | 0.83 | HTR1A (0.54) | HTR7QPCTHTR1ADRD3DRD2 | |
| SCHEMBL11171069 | 0.83 | QPCT (0.52) | QPCTHTR1ADRD3DRD2USP2 | |
| SCHEMBL11173613 | 0.83 | MCHR1 (0.66) | QPCTHTR1ADRD2USP2ALDH1A1 | |
| SCHEMBL11198528 | 0.83 | ALDH1A1 (0.60) | QPCTHTR1AUSP2ALDH1A1LMNA | |
| SCHEMBL9428295 | 0.82 | KIT (0.46) | HTR1ADRD3DRD2HRH1KIT | |
| SCHEMBL11176687 | 0.82 | MCHR1 (0.60) | QPCTHTR1ADRD2USP2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL9428988 | 0.82 | MAPT (0.45) | HTR7HTR1ADRD3DRD2HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4413006-A | N-Aryl-N-phenoxy-alkyl-piperazine compounds useful in decreasing intracranial pressure | TANABE SEIYAKU CO., LTD. (JP) | 1983-11-01 | — | — | US | disclosed |
| EP-0034284-B1 | PIPERAZINE DERIVATIVE, PROCESSES FOR PREPARING THE SAME AND THERAPEUTIC COMPOSITIONS CONTAINING IT | Tanabe Seiyaku Co., Ltd. (JP) | 1983-10-05 | — | — | EP | disclosed |
| EP-0034284-A2 | Piperazine derivative, processes for preparing the same and therapeutic compositions containing it | Tanabe Seiyaku Co., Ltd. (JP) | 1981-08-26 | — | — | EP | disclosed |