Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | ANPEP | P15144 | 1/20 | 0.34 |
| ▸ | SCN4A | P35499 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 4/20 | 0.33 |
| ▸ | SCN3A | Q9NY46 | 3/20 | 0.33 |
| ▸ | SCN1A | P35498 | 3/20 | 0.33 |
| ▸ | SCN5A | Q14524 | 3/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.33 |
| ▸ | MAOA | P21397 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27950619 | 0.83 | MAPT (0.41) | MAPTHTTCYP1A2CYP2C9MEN1 | |
| SCHEMBL10391083 | 0.81 | ATM (0.38) | MAPTHTTCYP1A2CYP2C9MEN1 | |
| SCHEMBL10391707 | 0.79 | SCN4A (0.46) | CYP1A2CYP2C9NFKB1SCN4ALMNA | |
| SCHEMBL10392041 | 0.79 | ALDH1A1 (0.39) | MAPTCYP1A2CYP2C9MEN1KMT2A | |
| SCHEMBL11171569 | 0.79 | MAPT (0.46) | MAPTHTTCYP1A2CYP2C9MEN1 | |
| SCHEMBL10391712 | 0.78 | TAAR1 (0.39) | MAPTHTTCYP1A2CYP2C9MEN1 | |
| SCHEMBL11176677 | 0.78 | ALOX12 (0.36) | MAPTHTTCYP1A2CYP2C9MEN1 | |
| Hydrochloric Acid SCHEMBL10392835 | 0.78 | ALDH1A1 (0.39) | MAPTCYP1A2CYP2C9MEN1KMT2A | |
| SCHEMBL10391112 | 0.76 | KAT2B (0.37) | MAPTHTTCYP1A2CYP2C9MEN1 | |
| Hydrochloric Acid SCHEMBL11170663 | 0.76 | ALOX12 (0.35) | MAPTHTTCYP1A2CYP2C9MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4369325-A | ANTIPHLOGISTIC AND DIURETIC ACTIVITY | EGYT GYOGYSZERVEGYESZETI GYAR (HU) | 1983-01-18 | — | — | US | disclosed |
| US-4284642-A | DIURETICS, ANTIPHLOGISTICS | EGYT GYOGYSZERVEGYESZETI GYAR (HU) | 1981-08-18 | — | — | US | disclosed |