Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.43 |
| ▸ | DHODH | Q02127 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.34 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.34 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10726473 | 0.85 | SRD5A2 (0.37) | HSP90AA1DHODHALDH1A1CTDSP1AKR1C3 | |
| SCHEMBL11177770 | 0.84 | AKR1C3 (0.38) | HSP90AA1DHODHALDH1A1CTDSP1AKR1C4 | |
| SCHEMBL51134 | 0.82 | TSHR (0.41) | HSP90AA1ALDH1A1HPGDHSD17B10KDM4E | |
| SCHEMBL2695636 | 0.81 | TRPA1 (0.47) | HSP90AA1ALDH1A1CTDSP1CA1CA2 | |
| SCHEMBL11164810 | 0.81 | AKR1B1 (0.36) | ALDH1A1CTDSP1KDM4EMEN1MAPT | |
| SCHEMBL10939109 | 0.81 | HSP90AA1 (0.45) | HSP90AA1ALDH1A1TP53HSD17B10MEN1 | |
| Hydrochloric Acid SCHEMBL10847736 | 0.80 | TRPA1 (0.46) | HSP90AA1ALDH1A1CTDSP1CA1CA2 | |
| SCHEMBL11181610 | 0.80 | KEAP1 (0.40) | ALDH1A1KDM4EMAPT | |
| SCHEMBL11165407 | 0.77 | MCL1 (0.35) | ALDH1A1MEN1MAPTKMT2ATRPA1 | |
| SCHEMBL11172708 | 0.77 | ALDH1A1 (0.48) | ALDH1A1TP53HSD17B10KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4385182-A | SENSITIZERS OR PHOTOINITIATORS | CIBA-GEIGY CORPORATION (US) | 1983-05-24 | — | — | US | disclosed |