Carbamic Acid

Carbamic Acid

SCHEMBL3412931

Cn1cnc2ccc(C(=O)c3ccccc3)cc21.NC(=O)O

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.50
SMN1; SMN2 Q16637 3/20 0.50
GLA P06280 1/20 0.50
KMT2A Q03164 1/20 0.49
FGFR1 P11362 2/20 0.48
HPGD P15428 3/20 0.46
RAB9A P51151 2/20 0.46
KDM4E B2RXH2 2/20 0.46
HTT P42858 1/20 0.46
HSD11B1 P28845 2/20 0.44
POLB P06746 1/20 0.44
ABL1 P00519 1/20 0.44
FABP6 P51161 1/20 0.44
F2 P00734 1/20 0.44
F10 P00742 1/20 0.44
PRSS1 P07477 1/20 0.44
GRM5 P41594 1/20 0.43
DYRK1A Q13627 1/20 0.43
CHRNA7 P36544 1/20 0.42
ATM Q13315 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Carbamic Acid SCHEMBL3434151 0.82 NPC1 (0.51) ALDH1A1SMN1; SMN2KMT2AFGFR1HPGD
SCHEMBL11171 0.82 SMN1; SMN2 (0.50) ALDH1A1SMN1; SMN2KMT2AFGFR1HPGD
SCHEMBL1869730 0.81 FGFR1 (0.60) ALDH1A1SMN1; SMN2KMT2AFGFR1HPGD
Carbamic Acid SCHEMBL1758683 0.79 EGLN3 (0.53) ALDH1A1SMN1; SMN2KMT2AFGFR1HPGD
SCHEMBL11114195 0.78 RAB9A (0.55) ALDH1A1SMN1; SMN2GLAKMT2AFGFR1
SCHEMBL29819602 0.77 ALDH1A1 (0.53) ALDH1A1SMN1; SMN2KMT2AFGFR1HPGD
SCHEMBL16602284 0.77 ALDH1A1 (0.53) ALDH1A1SMN1; SMN2KMT2AFGFR1HPGD
SCHEMBL7362182 0.76 F10 (0.49) SMN1; SMN2KMT2AHPGDRAB9AHSD11B1
SCHEMBL20570515 0.76 CHRNA7 (0.47) ALDH1A1SMN1; SMN2KMT2AFGFR1HPGD
SCHEMBL3491023 0.75 CHRNA7 (0.53) ALDH1A1SMN1; SMN2KMT2AFGFR1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2133318-B1 Building board NICHIHA KK (JP) 2010-12-22 EP disclosed
US-20090191251-A1 ANTIMICROBIAL MOLDED ARTICLE, LAMINATE, HEAT INSULATING MATERIAL AND SYNTHETIC LEATHER PRODUCT FUKATSU FUMIOKI 2009-07-30 US disclosed
US-7534485-B2 Building board NICHIHA CORPORATION (JP) 2009-05-19 US disclosed
US-20080233160-A1 Building board NICHIHA CORPORATION 2008-09-25 US disclosed
US-20080138385-A1 Antibacterial Composition, Antibacterial Molding, Solution Containing Antibacterial Composition, Detergent, Surface of Tatami Mat and Tatami Mat IDEMITSU TECHNOFINE CO., LTD. (JP) 2008-06-12 US disclosed
EP-1779727-A1 ANTIBACTERIAL COMPOSITION, ANTIBACTERIAL MOLDING, SOLUTION CONTAINING ANTIBACTERIAL COMPOSITION, DETERGENT, SURFACE OF TATAMI MAT AND TATAMI MAT Idemitsu Technofine Co. Ltd (JP) 2007-05-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080138385-A1 Antibacterial Composition, Antibacterial Molding, Solution Containing Antibacterial Composition, Detergent, Surface of Tatami Mat and Tatami Mat TPMT, KAT5, CARM1 ALDH1A1 1896/4885SMN1; SMN2 1234/4885GLA 2263/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.