Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 10/20 | 0.53 |
| ▸ | CNR1 | P21554 | 6/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | HPGDS | O60760 | 1/20 | 0.46 |
| ▸ | THRA | P10827 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.44 |
| ▸ | CCR6 | P51684 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.44 |
| ▸ | PLK1 | P53350 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1869452 | 0.85 | CNR2 (0.54) | CNR2CNR1CYP2C9HPGDSGLA | |
| SCHEMBL7905505 | 0.85 | CNR2 (0.54) | CNR2CNR1CYP2C9HPGDSTHRA | |
| SCHEMBL5232608 | 0.83 | CNR2 (0.53) | CNR2CNR1CYP2C9HPGDSTHRA | |
| SCHEMBL15693354 | 0.81 | MAPT (0.46) | CNR2CNR1ALDH1A1LMNAMAPT | |
| SCHEMBL9169708 | 0.81 | L3MBTL1 (0.50) | CNR2CNR1CYP2C9L3MBTL1ALDH1A1 | |
| SCHEMBL29378631 | 0.80 | ALDH1A1 (0.54) | CNR2GLAL3MBTL1ALDH1A1LMNA | |
| SCHEMBL50817 | 0.80 | ALDH1A1 (0.54) | CNR2GLAL3MBTL1ALDH1A1LMNA | |
| SCHEMBL28992535 | 0.79 | HCRTR1 (0.62) | GLAL3MBTL1ALDH1A1LMNAHPGD | |
| SCHEMBL20520346 | 0.78 | THRA (0.53) | CNR2CNR1CYP2C9HPGDSTHRA | |
| SCHEMBL18911045 | 0.78 | CNR2 (0.48) | CNR2CNR1CYP2C9HPGDSTHRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0010994-B1 | PROCESS FOR PRODUCING SUBSTITUTED NAPHTHALIC ACID COMPOUNDS | BRENT CHEMICALS INTERNATIONAL PLC (GB) | 1983-04-20 | — | — | EP | disclosed |
| US-4371694-A | DENITRATION, AMINATION | BRENT CHEMICALS INTERNATIONAL LIMITED (GB) | 1983-02-01 | — | — | US | disclosed |
| WO-1980000963-A1 | AROMATIC COMPOUNDS AND THEIR MANUFACTURE | BRENT CHEMICALS INT (GB) | 1980-05-15 | — | — | WO | disclosed |
| EP-0010994-A1 | Process for producing substituted naphthalic acid compounds | BRENT CHEMICALS INTERNATIONAL PLC (GB) | 1980-05-14 | — | — | EP | disclosed |