Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 2/20 | 0.49 |
| ▸ | F13A1 | P00488 | 3/20 | 0.47 |
| ▸ | TGM2 | P21980 | 3/20 | 0.47 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11171430 | 0.84 | CAPN1 (0.51) | F13A1TGM2KMT2AMEN1POLB | |
| SCHEMBL11194253 | 0.81 | HCAR2 (0.55) | RAB9AKMT2AMEN1MAPTMAPK1 | |
| SCHEMBL1034658 | 0.79 | MGLL (0.74) | MGLLLRRK2RAB9ANPC1HPGD | |
| SCHEMBL19597031 | 0.76 | PTPRB (0.46) | F13A1TGM2RAB9ANPC1HPGD | |
| SCHEMBL16276103 | 0.76 | PTPRB (0.46) | F13A1TGM2RAB9ANPC1HPGD | |
| SCHEMBL11173177 | 0.76 | HCAR2 (0.40) | MGLLRAB9AALDH1A1MAPTMAPK1 | |
| SCHEMBL11174768 | 0.76 | ALDH1A1 (0.47) | RAB9ANPC1HPGDKMT2AALDH1A1 | |
| SCHEMBL6816419 | 0.74 | FABP7 (0.54) | RAB9ANPC1KMT2AALDH1A1TDP1 | |
| SCHEMBL2386510 | 0.74 | FABP7 (0.54) | RAB9ANPC1KMT2AALDH1A1TDP1 | |
| SCHEMBL2386506 | 0.74 | FABP7 (0.54) | RAB9ANPC1KMT2AALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4387238-A | ANTIINFLAMMATORY, HYPOTENSIVE AGENTS, ENZYME INHIBITORS, ANTISPASMODIC AGENTS | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 1983-06-07 | — | — | US | disclosed |