Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.55 |
| ▸ | MMP1 | P03956 | 1/20 | 0.51 |
| ▸ | MMP2 | P08253 | 1/20 | 0.51 |
| ▸ | MMP9 | P14780 | 1/20 | 0.51 |
| ▸ | MMP12 | P39900 | 1/20 | 0.51 |
| ▸ | IDO1 | P14902 | 2/20 | 0.49 |
| ▸ | AGXT | P21549 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | STAT1 | P42224 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 6/20 | 0.47 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11173174 | 0.81 | MGLL (0.49) | KDM4ERAB9AMAPTMAPK1MEN1 | |
| SCHEMBL11173177 | 0.80 | HCAR2 (0.40) | HCAR2MMP1MMP2MMP9MMP12 | |
| SCHEMBL1787511 | 0.80 | HCAR2 (0.64) | HCAR2MMP1MMP2MMP9MMP12 | |
| SCHEMBL28707037 | 0.80 | HCAR2 (0.64) | HCAR2MMP1MMP2MMP9MMP12 | |
| SCHEMBL21432099 | 0.79 | HCAR2 (0.49) | HCAR2MMP1MMP2MMP9MMP12 | |
| SCHEMBL1787512 | 0.78 | HCAR2 (0.67) | HCAR2MMP1MMP2MMP9MMP12 | |
| SCHEMBL6901937 | 0.77 | HCAR2 (0.60) | HCAR2MMP1MMP2MMP9MMP12 | |
| SCHEMBL5049642 | 0.77 | HCAR2 (0.60) | HCAR2MMP1MMP2MMP9MMP12 | |
| SCHEMBL29747227 | 0.77 | HCAR2 (0.60) | HCAR2MMP1MMP2MMP9MMP12 | |
| SCHEMBL3764644 | 0.77 | ALDH1A1 (0.61) | HCAR2MMP1MMP2MMP9MMP12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4393228-A | THIOL PROTEASE INHIBITORS, ANTIINFLAMMATORY | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 1983-07-12 | — | — | US | disclosed |