Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | PRKCA | P17252 | 1/20 | 0.40 |
| ▸ | AKT1 | P31749 | 1/20 | 0.40 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.40 |
| ▸ | MDM4 | O15151 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | NT5E | P21589 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11176233 | 1.00 | POLB (0.55) | POLBLMNAKMT2AALDH1A1TP53 | |
| SCHEMBL11170133 | 0.94 | POLB (0.51) | POLBLMNAKMT2AALDH1A1TP53 | |
| SCHEMBL11170141 | 0.94 | POLB (0.51) | POLBLMNAKMT2AALDH1A1TP53 | |
| SCHEMBL22607620 | 0.92 | POLB (0.50) | POLBLMNAKMT2AALDH1A1TP53 | |
| SCHEMBL8038810 | 0.88 | POLB (0.63) | POLBLMNAKMT2AALDH1A1CYP3A4 | |
| SCHEMBL24804649 | 0.85 | LMNA (0.52) | POLBLMNAKMT2AALDH1A1CYP2C19 | |
| SCHEMBL9332856 | 0.85 | LMNA (0.52) | POLBLMNAKMT2AALDH1A1CYP2C19 | |
| SCHEMBL29865166 | 0.85 | LMNA (0.52) | POLBLMNAKMT2AALDH1A1CYP2C19 | |
| SCHEMBL9332848 | 0.85 | LMNA (0.52) | POLBLMNAKMT2AALDH1A1CYP2C19 | |
| SCHEMBL10604737 | 0.84 | POLB (0.59) | POLBLMNAKMT2AALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4391800-A | Immunologically active peptidyl disaccharides and methods of preparation | MERCK & CO., INC. (US) | 1983-07-05 | — | — | US | disclosed |