Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | P4HB | P07237 | 1/20 | 0.44 |
| ▸ | PDIA4 | P13667 | 1/20 | 0.44 |
| ▸ | PDIA3 | P30101 | 1/20 | 0.44 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.43 |
| ▸ | PRKCA | P17252 | 1/20 | 0.43 |
| ▸ | AKT1 | P31749 | 1/20 | 0.43 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9332848 | 1.00 | LMNA (0.52) | LMNAPOLBKMT2ATSHRCYP2D6 | |
| SCHEMBL24804649 | 1.00 | LMNA (0.52) | LMNAPOLBKMT2ATSHRCYP2D6 | |
| SCHEMBL9332856 | 1.00 | LMNA (0.52) | LMNAPOLBKMT2ATSHRCYP2D6 | |
| SCHEMBL25736465 | 0.92 | LMNA (0.48) | LMNAPOLBKMT2ATSHRCYP2D6 | |
| SCHEMBL8002809 | 0.92 | CYP3A4 (0.46) | LMNAPOLBKMT2ATSHRCYP2D6 | |
| SCHEMBL827827 | 0.89 | NT5E (0.47) | LMNAPOLBKMT2ATSHRCYP2D6 | |
| SCHEMBL827826 | 0.89 | NT5E (0.47) | LMNAPOLBKMT2ATSHRCYP2D6 | |
| SCHEMBL17456128 | 0.89 | NT5E (0.48) | LMNAPOLBKMT2ACYP2D6ALDH1A1 | |
| SCHEMBL17456127 | 0.89 | NT5E (0.48) | LMNAPOLBKMT2ACYP2D6ALDH1A1 | |
| SCHEMBL8699189 | 0.89 | TSHR (0.50) | LMNAPOLBKMT2ATSHRCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12129274-B2 | Modular synthesis of aminoglycosides | REVAGENIX, INC. (US) | 2024-10-29 | — | — | US | disclosed |
| US-11673907-B2 | Modular synthesis of aminoglycosides | REVAGENIX, INC. (US) | 2023-06-13 | — | — | US | disclosed |
| US-20230167148-A1 | MODULAR SYNTHESIS OF AMINOGLYCOSIDES | REVAGENIX, INC. | 2023-06-01 | — | — | US | disclosed |
| US-20220411456-A1 | MODULAR SYNTHESIS OF AMINOGLYCOSIDES | REVAGENIX, INC. (US) | 2022-12-29 | — | — | US | disclosed |
| US-11414450-B1 | Aminoglycosides and uses thereof | REVAGENIX, INC. (US) | 2022-08-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11673907-B2 | Modular synthesis of aminoglycosides | MRPL21, COASY, AARS1 | LMNA 2679/4885POLB 494/4885KMT2A 3736/4885 |
| US-12129274-B2 | Modular synthesis of aminoglycosides | MRPL21, COASY, AARS1 | LMNA 2679/4885POLB 494/4885KMT2A 3736/4885 |
| US-20230167148-A1 | MODULAR SYNTHESIS OF AMINOGLYCOSIDES | MRPL21, COASY, AARS1 | LMNA 2679/4885POLB 494/4885KMT2A 3736/4885 |
| US-20220411456-A1 | MODULAR SYNTHESIS OF AMINOGLYCOSIDES | MRPL21, COASY, AARS1 | LMNA 2679/4885POLB 494/4885KMT2A 3736/4885 |
| US-11414450-B1 | Aminoglycosides and uses thereof | ALPI, ATP6V1B1, RPN2 | LMNA 790/4885POLB 45/4885KMT2A 4091/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.